Myoepithelial carcinoma of the submandibular gland: report of a case with multiple cutaneous metastases

• Published in: Oral surgery, oral medicine, oral pathology, oral radiology and endodontics Vol. 106; no. 2; pp. e26 - e29
• Main Authors: Cosentino, Tiago Barra, MD, Brazão-Silva, Marco Túllio, DDS, Souza, Kelen Christine do Nascimento, DDS, PhD, de Faria, Paulo Rogério, DDS, PhD, de Moraes, Sávio, MD, Loyola, Adriano Mota, DDS, PhD, da Silva, Sindeval José, MD, MsC, Cardoso, Sérgio Vitorino, DDS, PhD
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01-08-2008
• Subjects: Aged; Carcinoma - diagnosis; Carcinoma - pathology; Carcinoma - secondary; Dentistry; Fatal Outcome; Female; Follow-Up Studies; Humans; Mitosis; Necrosis; Neoplasm Invasiveness; Skin Neoplasms - secondary; Submandibular Gland Neoplasms - diagnosis; Submandibular Gland Neoplasms - pathology; Surgery
• ISSN: 1079-2104; 1528-395X
• DOI: 10.1016/j.tripleo.2008.04.011

Myoepithelial carcinoma is a rare and aggressive neoplasm of the salivary glands. One-third of the patients may develop regional distant metastases, and lungs and kidneys have been regarded as the most usual sites for implantation. There is, however, little information on the metastatic behavior of this malignancy. We report the first case of patient with multiple cutaneous metastases from a myoepithelial carcinoma of the submandibular gland, which depicted a very aggressive clinical course.