Performance of the OraQuick HCV rapid antibody test for screening exposed patients in a hepatitis C outbreak investigation

Performance of the OraQuick HCV rapid antibody test for screening exposed patients in a hepatitis C outbreak investigation

During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were verified by a standard enzyme immunoassay (EIA). Of 1,157 persons, 1,149 (99.3%) exhibited concordant results between the two tests (16 positive, 1,133 negat...

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Published in:Journal of clinical microbiology Vol. 52; no. 7; pp. 2650 - 2652
Main Authors: Gao, Fengxiang, Talbot, Elizabeth A, Loring, Carol H, Power, Jill J, Dionne-Odom, Jodie, Alroy-Preis, Sharon, Jackson, Patricia, Bean, Christine L
Format: Journal Article
Language:English
Published: United States American Society for Microbiology 01-07-2014
Subjects:
Clinical Laboratory Techniques - methods
Cross Infection - diagnosis
Cross Infection - epidemiology
Disease Outbreaks
Female
Hepatitis C - diagnosis
Hepatitis C - epidemiology
Hepatitis C Antibodies - blood
Hepatitis C virus
Humans
Male
Mass Screening - methods
Predictive Value of Tests
Sensitivity and Specificity
Virology
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Abstract During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were verified by a standard enzyme immunoassay (EIA). Of 1,157 persons, 1,149 (99.3%) exhibited concordant results between the two tests (16 positive, 1,133 negative). The sensitivity, specificity, positive predictive value, and negative predictive value were 94.1%, 99.5%, 72.7%, and 99.9%, respectively. OraQuick performed well as a screening test during an outbreak investigation and could be integrated into future hepatitis C virus (HCV) outbreak testing algorithms.
AbstractList ABSTRACT During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were verified by a standard enzyme immunoassay (EIA). Of 1,157 persons, 1,149 (99.3%) exhibited concordant results between the two tests (16 positive, 1,133 negative). The sensitivity, specificity, positive predictive value, and negative predictive value were 94.1%, 99.5%, 72.7%, and 99.9%, respectively. OraQuick performed well as a screening test during an outbreak investigation and could be integrated into future hepatitis C virus (HCV) outbreak testing algorithms.
During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were verified by a standard enzyme immunoassay (EIA). Of 1,157 persons, 1,149 (99.3%) exhibited concordant results between the two tests (16 positive, 1,133 negative). The sensitivity, specificity, positive predictive value, and negative predictive value were 94.1%, 99.5%, 72.7%, and 99.9%, respectively. OraQuick performed well as a screening test during an outbreak investigation and could be integrated into future hepatitis C virus (HCV) outbreak testing algorithms.
Author Power, Jill J
Alroy-Preis, Sharon
Bean, Christine L
Talbot, Elizabeth A
Dionne-Odom, Jodie
Gao, Fengxiang
Loring, Carol H
Jackson, Patricia
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Snippet During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were verified by a...
ABSTRACT During a nosocomial hepatitis C outbreak, emergency public clinics employed the OraQuick HCV rapid antibody test on site, and all results were...
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SubjectTerms Clinical Laboratory Techniques - methods
Cross Infection - diagnosis
Cross Infection - epidemiology
Disease Outbreaks
Female
Hepatitis C - diagnosis
Hepatitis C - epidemiology
Hepatitis C Antibodies - blood
Hepatitis C virus
Humans
Male
Mass Screening - methods
Predictive Value of Tests
Sensitivity and Specificity
Virology
Title Performance of the OraQuick HCV rapid antibody test for screening exposed patients in a hepatitis C outbreak investigation
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