Loss of maspin is a helpful prognosticator in colorectal cancer: a tissue microarray analysis

Mammary serpin (Maspin) belongs to the serine protease inhibitor (serpin) superfamily and has been identified as a tumor suppressor. In addition, a p53-dependent regulatory pathway of maspin in human cancer has been indicated. The role of maspin in the tumorigenesis and progression of colorectal can...

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Bibliographic Details
Published in:	Pathology, research and practice Vol. 200; no. 11; pp. 783 - 790
Main Author:	Boltze, Carsten
Format:	Journal Article
Language:	English
Published:	Germany Elsevier GmbH 01-01-2005
Subjects:	Adenocarcinoma - metabolism Adenocarcinoma - mortality Adenocarcinoma - secondary Adenocarcinoma - surgery Adenoma - metabolism Adenoma - mortality Adenoma - pathology Adenoma - surgery Aged Aged, 80 and over Biomarkers, Tumor - metabolism Colorectal carcinoma Colorectal Neoplasms - metabolism Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Disease-Free Survival Female Genes, Tumor Suppressor Humans Immunoenzyme Techniques Male Maspin Middle Aged Neoplasm Staging Prognosis Serine Proteinase Inhibitors - metabolism Serpins - metabolism Survival Rate Tissue Array Analysis Maspin Colorectal carcinoma Prognosis
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