Association between methylene tetrahydrofolate reductase and glutathione S-transferase M1 gene polymorphisms and chronic myeloid leukemia in a Brazilian population

Chronic myeloid leukemia is a hematopoietic stem cell disorder that causes uncontrolled proliferation of white blood cells. Although the clinical and biological aspects are well documented, little is known about individual susceptibility to this disease. We conducted a case-control study analyzing t...

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Bibliographic Details

Published in:	Genetics and molecular research Vol. 11; no. 2; pp. 1013 - 1026
Main Authors:	Lordelo, G S, Miranda-Vilela, A L, Akimoto, A K, Alves, P C Z, Hiragi, C O, Nonino, A, Daldegan, M B, Klautau-Guimarães, M N, Grisolia, C K
Format:	Journal Article
Language:	English
Published:	Brazil 01-01-2012
Subjects:	Adult Brazil Female Genetics, Population Glutathione Transferase - genetics Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Polymorphism, Genetic Brazil
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