The influence of prenatal and/or postnatal exposure to lead on behavior of preweanling mice

Binghamton Heterogeneous (HET) Stock mice received prenatal exposure to either water or a 0.5% lead acetate solution via their biological dam. At birth, litters were cross-fostered so that they were postnatally exposed to either water or lead via their foster dam. Early preweaning measures of square...

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Bibliographic Details
Published in:	Physiology & behavior Vol. 45; no. 4; p. 711
Main Authors:	Draski, L J, Burright, R G, Donovick, P J
Format:	Journal Article
Language:	English
Published:	United States 01-04-1989
Subjects:	Age Factors Animals Animals, Suckling Behavior, Animal - drug effects Exploratory Behavior - drug effects Female Lead - blood Lead - pharmacology Male Mice - blood Mice - growth & development Motor Activity - drug effects Pregnancy Prenatal Exposure Delayed Effects
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Summary:	Binghamton Heterogeneous (HET) Stock mice received prenatal exposure to either water or a 0.5% lead acetate solution via their biological dam. At birth, litters were cross-fostered so that they were postnatally exposed to either water or lead via their foster dam. Early preweaning measures of square crossing and standups in an open field and time to return to home cage nest showed that the effects of lead on behavior depend on: the developmental stage(s) during which the individual is exposed to the toxin, as well as age and conditions when tested.
ISSN:	0031-9384
DOI:	10.1016/0031-9384(89)90283-7