Evaluation of murine lymphocyte membrane potential, intracellular free calcium, and interleukin-2 receptor expression upon exposure to 1,1-dimethylhydrazine

The effects of 1,1-dimethylhydrazine (UDMH) on several early events associated with lymphocyte activation were examined. The concentration of intracellular calcium ([Ca2+]i) and membrane potential of murine lymphocytes were found to be altered upon exposure to UDMH; [Ca2+]i was increased in murine t...

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Bibliographic Details
Published in:	Toxicology letters Vol. 61; no. 1; p. 27
Main Authors:	Frazier, Jr, D E, Tarr, M J, Olsen, R G
Format:	Journal Article
Language:	English
Published:	Netherlands 01-06-1992
Subjects:	Animals Calcium - metabolism Cell Division - drug effects Concanavalin A - pharmacology Dimethylhydrazines - pharmacology Female Flow Cytometry Lymphocyte Activation - drug effects Lymphocytes - drug effects Lymphocytes - metabolism Membrane Potentials Mice Mice, Inbred BALB C Receptors, Interleukin-2 - drug effects Receptors, Interleukin-2 - metabolism Spleen - cytology Thymus Gland - cytology Time Factors
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