Insight into the relationship between brain/behavioral speed and variability in patients with minimal hepatic encephalopathy

Highlights • Single-trial P300 latency increases and amplitude decreases along reaction times (RTs) distribution. • The relationship between P300 and RTs disappears in patients with Minimal hepatic encephalopathy (MHE). • Temporal overlap between stimulus and response selection is related to both RT...

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Bibliographic Details
Published in:	Clinical neurophysiology Vol. 125; no. 2; pp. 287 - 297
Main Authors:	Schiff, S, D’Avanzo, C, Cona, G, Goljahani, A, Montagnese, S, Volpato, C, Gatta, A, Sparacino, G, Amodio, P, Bisiacchi, P
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ireland Ltd 01-02-2014
Subjects:	Adult Bayes Theorem Brain - physiopathology Conflict (Psychology) Evoked Potentials - physiology Female Hepatic Encephalopathy - physiopathology Humans Intra-individual variability of RTs Liver Cirrhosis - physiopathology Male Middle Aged Minimal hepatic encephalopathy Neurology Neuropsychological Tests Reaction Time - physiology Severity of Illness Index Simon task Single-trial P300 Intra-individual variability of RTs Minimal hepatic encephalopathy Simon task Single-trial P300
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Summary:	Highlights • Single-trial P300 latency increases and amplitude decreases along reaction times (RTs) distribution. • The relationship between P300 and RTs disappears in patients with Minimal hepatic encephalopathy (MHE). • Temporal overlap between stimulus and response selection is related to both RTs speed and variability.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2013.08.004