The impact of withholding nitrous oxide in labour during the COVID‐19 pandemic on maternal and neonatal outcomes

Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine...

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Published in:Australian & New Zealand journal of obstetrics & gynaecology Vol. 62; no. 6; pp. 910 - 914
Main Authors: Froessler, Bernd, Malek, Michaela, Jila, Mathonsi, Parange, Anupam, Kelly, Thu‐Lan
Format: Journal Article
Language:English
Published: Australia John Wiley and Sons Inc 01-12-2022
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Abstract Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine the impact of withholding nitrous oxide for labour analgesia, during the COVID‐19 pandemic, on epidural rates, opioid analgesia use, and maternal and neonatal outcomes. Withholding nitrous oxide for labour analgesia did not alter epidural rates but did significantly increase opioid analgesia use. Caesarean section rates, post‐partum blood loss and neonatal APGAR scores did not change.
AbstractList Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine the impact of withholding nitrous oxide for labour analgesia, during the COVID‐19 pandemic, on epidural rates, opioid analgesia use, and maternal and neonatal outcomes. Withholding nitrous oxide for labour analgesia did not alter epidural rates but did significantly increase opioid analgesia use. Caesarean section rates, post‐partum blood loss and neonatal APGAR scores did not change.
Author Jila, Mathonsi
Parange, Anupam
Froessler, Bernd
Malek, Michaela
Kelly, Thu‐Lan
AuthorAffiliation 4 Clinical and Health Sciences, Quality Use of Medicines Pharmacy Research Centre University of South Australia Adelaide South Australia Australia
1 Department of Anaesthesia Lyell McEwin Hospital Adelaide South Australia Australia
2 Discipline of Acute Care Medicine Adelaide Medical School The University of Adelaide Adelaide South Australia Australia
3 Department of Obstetrics and Gynaecology Lyell McEwin Hospital Adelaide South Australia Australia
AuthorAffiliation_xml – name: 1 Department of Anaesthesia Lyell McEwin Hospital Adelaide South Australia Australia
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CitedBy_id crossref_primary_10_1016_j_bpa_2024_04_007
crossref_primary_10_36290_aim_2022_051
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crossref_primary_10_1111_1471_0528_17873
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Issue 6
Keywords greenhouse gases
epidural
Covid-19
nitrous oxide
adverse birth outcomes
analgesia
Language English
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2022 The Authors. Australian and New Zealand Journal of Obstetrics and Gynaecology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Obstetricians and Gynaecologists.
This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
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Snippet Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of...
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SubjectTerms adverse birth outcomes
analgesia
Analgesia, Epidural
Analgesia, Obstetrical
Analgesics, Opioid - therapeutic use
Cesarean Section
COVID-19
epidural
Female
greenhouse gases
Humans
Infant, Newborn
Nitrous Oxide
Pandemics - prevention & control
Pregnancy
Short Communication
Short Communications
Title The impact of withholding nitrous oxide in labour during the COVID‐19 pandemic on maternal and neonatal outcomes
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fajo.13577
https://www.ncbi.nlm.nih.gov/pubmed/35781873
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