The impact of withholding nitrous oxide in labour during the COVID‐19 pandemic on maternal and neonatal outcomes
Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine...
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Published in: | Australian & New Zealand journal of obstetrics & gynaecology Vol. 62; no. 6; pp. 910 - 914 |
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John Wiley and Sons Inc
01-12-2022
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Abstract | Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine the impact of withholding nitrous oxide for labour analgesia, during the COVID‐19 pandemic, on epidural rates, opioid analgesia use, and maternal and neonatal outcomes. Withholding nitrous oxide for labour analgesia did not alter epidural rates but did significantly increase opioid analgesia use. Caesarean section rates, post‐partum blood loss and neonatal APGAR scores did not change. |
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AbstractList | Nitrous oxide is commonly used in Australia for labour analgesia. Its use in labour is potentially associated with aerosol generation. During the first wave of the COVID‐19 pandemic of 2020, nitrous oxide was suspended on many birthing units to reduce the risk of transmission. We aimed to determine the impact of withholding nitrous oxide for labour analgesia, during the COVID‐19 pandemic, on epidural rates, opioid analgesia use, and maternal and neonatal outcomes. Withholding nitrous oxide for labour analgesia did not alter epidural rates but did significantly increase opioid analgesia use. Caesarean section rates, post‐partum blood loss and neonatal APGAR scores did not change. |
Author | Jila, Mathonsi Parange, Anupam Froessler, Bernd Malek, Michaela Kelly, Thu‐Lan |
AuthorAffiliation | 4 Clinical and Health Sciences, Quality Use of Medicines Pharmacy Research Centre University of South Australia Adelaide South Australia Australia 1 Department of Anaesthesia Lyell McEwin Hospital Adelaide South Australia Australia 2 Discipline of Acute Care Medicine Adelaide Medical School The University of Adelaide Adelaide South Australia Australia 3 Department of Obstetrics and Gynaecology Lyell McEwin Hospital Adelaide South Australia Australia |
AuthorAffiliation_xml | – name: 1 Department of Anaesthesia Lyell McEwin Hospital Adelaide South Australia Australia – name: 3 Department of Obstetrics and Gynaecology Lyell McEwin Hospital Adelaide South Australia Australia – name: 4 Clinical and Health Sciences, Quality Use of Medicines Pharmacy Research Centre University of South Australia Adelaide South Australia Australia – name: 2 Discipline of Acute Care Medicine Adelaide Medical School The University of Adelaide Adelaide South Australia Australia |
Author_xml | – sequence: 1 givenname: Bernd orcidid: 0000-0003-3755-8609 surname: Froessler fullname: Froessler, Bernd email: bernd.froessler@sa.gov.au, bernd.froessler@adelaide.edu.au organization: The University of Adelaide – sequence: 2 givenname: Michaela surname: Malek fullname: Malek, Michaela organization: Lyell McEwin Hospital – sequence: 3 givenname: Mathonsi surname: Jila fullname: Jila, Mathonsi organization: Lyell McEwin Hospital – sequence: 4 givenname: Anupam surname: Parange fullname: Parange, Anupam organization: Lyell McEwin Hospital – sequence: 5 givenname: Thu‐Lan surname: Kelly fullname: Kelly, Thu‐Lan organization: University of South Australia |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35781873$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1213/ANE.0000000000001680 10.1002/uog.23107 10.1016/j.ajog.2021.05.016 10.1213/ANE.0000000000004856 10.1177/0310057X19884075 10.1213/ANE.0b013e3181fe02c2 10.1111/jmwh.13124 10.1055/s-0040-1709689 10.1016/j.jclinane.2017.04.005 10.1016/j.bja.2021.10.021 10.5694/mja2.50574 10.1016/S2542-5196(17)30180-8 10.1016/j.ajog.2020.03.021 10.1016/j.jclinane.2016.07.019 10.1016/j.ajogmf.2020.100111 10.1136/bmj-2021-067696 10.1016/S0140-6736(21)00869-2 10.1093/bmb/ldx050 10.1136/bmj.n2342 |
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Keywords | greenhouse gases epidural Covid-19 nitrous oxide adverse birth outcomes analgesia |
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SubjectTerms | adverse birth outcomes analgesia Analgesia, Epidural Analgesia, Obstetrical Analgesics, Opioid - therapeutic use Cesarean Section COVID-19 epidural Female greenhouse gases Humans Infant, Newborn Nitrous Oxide Pandemics - prevention & control Pregnancy Short Communication Short Communications |
Title | The impact of withholding nitrous oxide in labour during the COVID‐19 pandemic on maternal and neonatal outcomes |
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