Characterization and electrocatalytic properties of Prussian blue electrochemically deposited on nano-Au/PAMAM dendrimer-modified gold electrode

• Published in: Biosensors & bioelectronics Vol. 23; no. 10; pp. 1519 - 1526
• Main Authors: Li, Nian Bing, Park, Jun Hui, Park, Kyungsoon, Kwon, Seong Jung, Shin, Hyunkyung, Kwak, Juhyoun
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 15-05-2008; Elsevier Science
• Subjects: Biological and medical sciences; Biosensing Techniques - instrumentation; Biosensing Techniques - methods; Biotechnology; Catalysis; Coated Materials, Biocompatible - chemistry; Dendrimers; Electric Conductivity; Electrochemical deposition; Electrochemistry - instrumentation; Electrochemistry - methods; Equipment Design; Equipment Failure Analysis; Ferrocyanides - chemistry; Fundamental and applied biological sciences. Psychology; Gold - chemistry; Hydrogen peroxide; Hydrogen Peroxide - analysis; Hydrogen Peroxide - chemistry; Methods. Procedures. Technologies; Microelectrodes; Nano-Au; Nanostructures - chemistry; Nanostructures - ultrastructure; Others; PAMAM dendrimer; Particle Size; Polyamines - chemistry; Prussian blue; Reproducibility of Results; Sensitivity and Specificity; Various methods and equipments; Nano-Au; Electrochemical deposition; Prussian blue; Hydrogen peroxide; PAMAM dendrimer; Characterization; Electrodes; Electrocatalysis; Gold; Branched polymer; Electrochemistry; Deposition
• ISSN: 0956-5663; 1873-4235
• DOI: 10.1016/j.bios.2008.01.009

Gold electrode was modified with 3-mercaptopropionic acid (MPA) and further reacted with poly(amidoamine) (PAMAM) dendrimer (generation 4.0) then attached the nano-Au to obtain films on which Prussian blue (PB) was electrochemically deposited to afford much wider pH adaptive range, much better electrochemical stability and excellent electrochemical response. The microstructure and electrochemical behavior of Au/MPA/PAMAM/nano-Au/PB electrode were investigated by scanning electron microscopy (SEM) and cyclic voltammetry. The electrochemical response of the Au/MPA/PAMAM/nano-Au/PB-modified electrode for the electrocatalytic reduction of hydrogen peroxide was investigated, and it was found that the sensitivity as well as the corresponding detection limits were improved as compared to the voltammetric response of a Au/PB-modified electrode and Au/MPA/PAMAM/PB electrode. Based on this, a new electrochemical sensor for determination of hydrogen peroxide has been developed.