Lung cancer management in limited resource settings: Guidelines for appropriate good care

• Published in: Radiotherapy and oncology Vol. 82; no. 2; pp. 123 - 131
• Main Authors: Macbeth, Fergus R, Abratt, Raymond P, Cho, Kwan H, Stephens, Richard J, Jeremic, Branislav
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01-02-2007
• Subjects: Antineoplastic Agents - economics; Antineoplastic Agents - therapeutic use; Carcinoma, Non-Small-Cell Lung - economics; Carcinoma, Non-Small-Cell Lung - therapy; Carcinoma, Small Cell - economics; Carcinoma, Small Cell - therapy; Chemotherapy; Clinical guidelines; Combined Modality Therapy; Cost-Benefit Analysis; Delivery of Health Care; Developing Countries; Hematology, Oncology and Palliative Medicine; Humans; Limited resource settings; Lung cancer; Lung Neoplasms - economics; Lung Neoplasms - therapy; Radiotherapy; Radiotherapy - economics; Radiotherapy Dosage; Clinical guidelines; Chemotherapy; Limited resource settings; Radiotherapy; Lung cancer
• ISSN: 0167-8140; 1879-0887
• DOI: 10.1016/j.radonc.2006.12.006

Abstract Lung cancer is a major cause of cancer death worldwide and is becoming an increasing problem in developing countries. It is important that, in countries where health care resources are limited, these resources are used most effectively and cost-effectively. The authors, with the support of the International Atomic Energy Agency, drew on existing evidence-based clinical guidelines, published systematic reviews and meta-analyses, as well as recent research publications, to summarise the current evidence and to make broad recommendations on the non-surgical treatment of patients with lung cancer. Tables were constructed which summarise the different treatment options for specific groups of patients, the increase in resource use for and the likely additional clinical benefit from each option. These tables can be used to assess the cost-effectiveness and appropriateness of different interventions in a particular health care system and to develop local clinical guidelines.