Cuprous oxide nanoparticles incorporated into a polymeric matrix embedded in fabrics to prevent spread of SARS-CoV-2

• Published in: International journal of pharmaceutics Vol. 636; p. 122790
• Main Authors: Usseglio, Nadina, Onnainty, Renée, Konigheim, Brenda, Aguilar, Javier, Petiti, Juan Pablo, Lingua, Giuliana, Leimgruber, Carolina, Bonafé Allende, Juan Cruz, Torres, Alicia, Granero, Gladys
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 05-04-2023
• Subjects: Bilayer coating; COVID-19 - prevention & control; Cuprous oxide hybrid nanoparticles; Fabrics/textile; Humans; Nanoparticles; Polymers; SARS-CoV-2; Textiles; Virucidal activity; Virucidal activity; Cuprous oxide hybrid nanoparticles; Bilayer coating; Fabrics/textile
• ISSN: 0378-5173; 1873-3476
• DOI: 10.1016/j.ijpharm.2023.122790

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•Cotton and PP fabrics coated with a chitosan matrix containing Cu2O@SDS NPs were developed.•The coating of the fabrics was carried out by using a dip-assisted layer-by-layer technology.•Low curing temperature and without expensive equipment or toxic chemicals were requirement.•The coating of fabrics developed provides a reduction in the infectivity of the SARS-CoV-2 virus.
This paper describes the development of a coating for cotton and polypropylene (PP) fabrics based on a polymeric matrix embedded with cuprous oxide nanoparticles (Cu2O@SDS NPs) in order to inactivate SARS-CoV-2 and manufactured by a simple process using a dip-assisted layer-by-layer technology, at low curing temperature and without the need for expensive equipment, capable of achieving disinfection rates of up to 99%. The polymeric bilayer coating makes the surface of the fabrics hydrophilic, enabling the transportation of the virus-infected droplets to achieve the rapid inactivation of SARS-CoV-2 by contact with the Cu2O@SDS NPs incorporated in the coated fabrics.