Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-β signaling in ovarian cancer

Ovarian cancer is resistant to the antiproliferative effects of transforming growth factor-beta (TGF-beta); however, the mechanism of this resistance remains unclear. We used oligonucleotide arrays to profile 37 undissected, 68 microdissected advanced-stage, and 14 microdissected early-stage papilla...

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Bibliographic Details
Published in:	Cancer research (Chicago, Ill.) Vol. 66; no. 17; pp. 8404 - 8412
Main Authors:	SUNDE, Jan S, DONNINGER, Howard, KONGMING WU, JOHNSON, Michael E, PESTELL, Richard G, ROSE, G. Scott, MOK, Samuel C, BRADY, John, BONOME, Tomas, BIRRER, Michael J
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA American Association for Cancer Research 01-09-2006
Subjects:	Biological and medical sciences Female Female genital diseases Gene Expression Profiling Genes, Reporter Gynecology. Andrology. Obstetrics Humans Medical sciences Neoplasm Staging Neoplasms, Cystic, Mucinous, and Serous - genetics Neoplasms, Cystic, Mucinous, and Serous - pathology Oligonucleotide Array Sequence Analysis Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Polymerase Chain Reaction RNA, Neoplasm - genetics RNA, Neoplasm - isolation & purification Signal Transduction Transforming Growth Factor beta - physiology Tumors Ovarian diseases Signal transduction Transforming growth factor β Ovary cancer Inhibitor Malignant tumor Gene expression Female genital diseases Gene expression profile
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