Rat bite as a cause of diabetic foot ulcer in sub‐Saharan Africa
There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist service in Dar es Salaam for diabetic foot ulcers (DFUs) between 1 January 1999 and 31 December 2016. Details from people presenting for the...
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Published in: | International wound journal Vol. 17; no. 4; pp. 897 - 899 |
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01-08-2020
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Abstract | There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist service in Dar es Salaam for diabetic foot ulcers (DFUs) between 1 January 1999 and 31 December 2016. Details from people presenting for the first time with an ulcer judged to be caused by rat bite were compared with those with from other causes of foot ulcer. There were 426 first recorded foot ulcer episodes (in 179 people) judged to be caused by rat bite. The affected population was significantly younger (mean 55.9 vs 57.5 years, P = .037) and had a lower body mass index (26.5 vs 27.9, P = .008) than controls with other types of foot ulcer. They also presented significantly sooner (7.8 vs 18.2 days, P < .001) and were more likely to heal (85.8 vs 5.5%, P < .001), even though there was also a trend towards an increased risk of death (9.1% vs 5.3%, P = .032). Rat bite is an uncommon cause of DFU, but is not rare. Although the incidence of ulcer healing is higher than in a general foot ulcer population, the incidence of death is also higher. |
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AbstractList | There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist service in Dar es Salaam for diabetic foot ulcers (DFUs) between 1 January 1999 and 31 December 2016. Details from people presenting for the first time with an ulcer judged to be caused by rat bite were compared with those with from other causes of foot ulcer. There were 426 first recorded foot ulcer episodes (in 179 people) judged to be caused by rat bite. The affected population was significantly younger (mean 55.9 vs 57.5 years, P = .037) and had a lower body mass index (26.5 vs 27.9, P = .008) than controls with other types of foot ulcer. They also presented significantly sooner (7.8 vs 18.2 days, P < .001) and were more likely to heal (85.8 vs 5.5%, P < .001), even though there was also a trend towards an increased risk of death (9.1% vs 5.3%, P = .032). Rat bite is an uncommon cause of DFU, but is not rare. Although the incidence of ulcer healing is higher than in a general foot ulcer population, the incidence of death is also higher. There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist service in Dar es Salaam for diabetic foot ulcers (DFUs) between 1 January 1999 and 31 December 2016. Details from people presenting for the first time with an ulcer judged to be caused by rat bite were compared with those with from other causes of foot ulcer. There were 426 first recorded foot ulcer episodes (in 179 people) judged to be caused by rat bite. The affected population was significantly younger (mean 55.9 vs 57.5 years, P = .037) and had a lower body mass index (26.5 vs 27.9, P = .008) than controls with other types of foot ulcer. They also presented significantly sooner (7.8 vs 18.2 days, P < .001) and were more likely to heal (85.8 vs 5.5%, P < .001), even though there was also a trend towards an increased risk of death (9.1% vs 5.3%, P = .032). Rat bite is an uncommon cause of DFU, but is not rare. Although the incidence of ulcer healing is higher than in a general foot ulcer population, the incidence of death is also higher. Abstract There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist service in Dar es Salaam for diabetic foot ulcers (DFUs) between 1 January 1999 and 31 December 2016. Details from people presenting for the first time with an ulcer judged to be caused by rat bite were compared with those with from other causes of foot ulcer. There were 426 first recorded foot ulcer episodes (in 179 people) judged to be caused by rat bite. The affected population was significantly younger (mean 55.9 vs 57.5 years, P = .037) and had a lower body mass index (26.5 vs 27.9, P = .008) than controls with other types of foot ulcer. They also presented significantly sooner (7.8 vs 18.2 days, P < .001) and were more likely to heal (85.8 vs 5.5%, P < .001), even though there was also a trend towards an increased risk of death (9.1% vs 5.3%, P = .032). Rat bite is an uncommon cause of DFU, but is not rare. Although the incidence of ulcer healing is higher than in a general foot ulcer population, the incidence of death is also higher. |
Author | Lutale, Janet K. Jeffcoate, William J. Archibald, Lennox K. Abbas, Zulfiqarali G. |
AuthorAffiliation | 3 Division of Infectious Disease & Global Medicine, Department of Medicine, College of Medicine University of Florida Florida USA 2 Department of Internal Medicine, Abbas Medical Centre Dar es Salaam Tanzania 4 Medical Physics and Clinical Engineering, Nottingham University Hospitals Trust Nottingham UK 1 Department of Internal Medicine, Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania |
AuthorAffiliation_xml | – name: 4 Medical Physics and Clinical Engineering, Nottingham University Hospitals Trust Nottingham UK – name: 1 Department of Internal Medicine, Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania – name: 2 Department of Internal Medicine, Abbas Medical Centre Dar es Salaam Tanzania – name: 3 Division of Infectious Disease & Global Medicine, Department of Medicine, College of Medicine University of Florida Florida USA |
Author_xml | – sequence: 1 givenname: Zulfiqarali G. surname: Abbas fullname: Abbas, Zulfiqarali G. organization: Department of Internal Medicine, Abbas Medical Centre – sequence: 2 givenname: Janet K. surname: Lutale fullname: Lutale, Janet K. organization: Department of Internal Medicine, Abbas Medical Centre – sequence: 3 givenname: Lennox K. surname: Archibald fullname: Archibald, Lennox K. organization: University of Florida – sequence: 4 givenname: William J. surname: Jeffcoate fullname: Jeffcoate, William J. email: william.jeffcoate@gmail.com organization: Medical Physics and Clinical Engineering, Nottingham University Hospitals Trust |
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Cites_doi | 10.1046/j.1464-5491.2002.00825.x 10.1177/1534734607313914 10.1007/s00125-006-0224-5 10.1007/s00125-006-0424-z 10.1111/j.1464-5491.2005.01488.x 10.1016/j.amjmed.2019.08.048 10.4103/jfmpc.jfmpc_569_19 10.1136/bmj.298.6677.868 |
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Keywords | Africa, diabetic foot ulcer, infection, neuropathy Rat bite |
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References | 2019; 8 2019 2008; 7 2016; 2016 2002; 19 2005; 22 2006; 49 1992; 40 1989; 298 e_1_2_8_2_1 Shridhar GR (e_1_2_8_3_1) 1992; 40 e_1_2_8_4_1 e_1_2_8_7_1 e_1_2_8_6_1 e_1_2_8_9_1 e_1_2_8_8_1 e_1_2_8_10_1 e_1_2_8_11_1 e_1_2_8_12_1 Jarial KD (e_1_2_8_5_1) 2016; 2016 |
References_xml | – volume: 22 start-page: 631 issue: 5 year: 2005 end-page: 633 article-title: Rodent bites on the feet of diabetes patients in Tanzania publication-title: Diabet Med – volume: 49 start-page: 2811 issue: 11 year: 2006 end-page: 2812 article-title: Comment on: Kalra B, Kalra S, Chatley G, Singh H. Rat bite as a cause of diabetic foot ulcer—a series of eight cases. Diabetologia. 49: 1452‐1453 publication-title: Diabetologia – volume: 298 start-page: 868 issue: 6677 year: 1989 article-title: Rat bites and diabetic foot in the West Indies publication-title: Brit Med J – volume: 7 start-page: 41 issue: 1 year: 2008 end-page: 44 article-title: Nonvenomous bite injuries of the foot: case reports and review of the literature publication-title: Int J Lower Extrem Wounds – volume: 40 start-page: 281 issue: 4 year: 1992 end-page: 282 article-title: Rat bites and diabetic foot ulcer publication-title: Journal Assoc Phys India – volume: 19 start-page: 895 issue: 11 year: 2002 end-page: 899 article-title: The epidemiology of diabetic limb sepsis: an African perspective publication-title: Diabet Med – year: 2019 article-title: Rat bites in the diabetic foot: clinical clues publication-title: Am J Med – volume: 49 start-page: 1452 issue: 6 year: 2006 end-page: 1453 article-title: Rat bite as a cause of diabetic foot ulcer—a series of eight cases publication-title: Diabetologia – volume: 2016 year: 2016 article-title: Rat bite ulcer in an insensate foot publication-title: BMJ Case Rep – volume: 8 start-page: 3068 issue: 9 year: 2019 end-page: 3070 article-title: An unusual cause of foot ulcer in a patient with diabetes mellitus publication-title: J Family Med Prim Care – ident: e_1_2_8_12_1 doi: 10.1046/j.1464-5491.2002.00825.x – ident: e_1_2_8_7_1 doi: 10.1177/1534734607313914 – ident: e_1_2_8_10_1 – volume: 40 start-page: 281 issue: 4 year: 1992 ident: e_1_2_8_3_1 article-title: Rat bites and diabetic foot ulcer publication-title: Journal Assoc Phys India contributor: fullname: Shridhar GR – ident: e_1_2_8_4_1 doi: 10.1007/s00125-006-0224-5 – ident: e_1_2_8_11_1 doi: 10.1007/s00125-006-0424-z – ident: e_1_2_8_2_1 doi: 10.1111/j.1464-5491.2005.01488.x – ident: e_1_2_8_9_1 doi: 10.1016/j.amjmed.2019.08.048 – volume: 2016 year: 2016 ident: e_1_2_8_5_1 article-title: Rat bite ulcer in an insensate foot publication-title: BMJ Case Rep contributor: fullname: Jarial KD – ident: e_1_2_8_6_1 doi: 10.4103/jfmpc.jfmpc_569_19 – ident: e_1_2_8_8_1 doi: 10.1136/bmj.298.6677.868 |
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Snippet | There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single specialist... Abstract There have been relatively few reports of foot ulcers in diabetes resulting from rat bite. The findings were derived from people attending a single... |
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SubjectTerms | Africa, diabetic foot ulcer, infection, neuropathy Original Rat bite |
Title | Rat bite as a cause of diabetic foot ulcer in sub‐Saharan Africa |
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