Growth inhibition and compensation in response to neonatal hypoxia in rats

Background: Hypoxia (Hx) is an important disease mechanism in prematurity, childhood asthma, and obesity. In children, Hx results in chronic inflammation. Methods: We investigated the effects of Hx (12% O 2 ) during postnatal days 2–20 in rats. Control groups were normoxic control (Nc), and normoxic...

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Bibliographic Details
Published in:	Pediatric research Vol. 74; no. 2; pp. 111 - 120
Main Authors:	Radom-Aizik, Shlomit, Zaldivar, Frank P., Nance, Dwight M., Haddad, Fadia, Cooper, Dan M., Adams, Gregory R.
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01-08-2013
Subjects:	Analysis of Variance Animals Animals, Newborn basic-science-investigation Blood Cell Count Cytokines - blood DNA Primers - genetics Female Gonadal Steroid Hormones - blood Heart Ventricles - growth & development Hypoxia - metabolism Hypoxia - physiopathology Intercellular Signaling Peptides and Proteins - blood Male Medicine Medicine & Public Health MicroRNAs - genetics Muscle, Skeletal - growth & development Organ Size - physiology Pediatric Surgery Pediatrics Pregnancy Rats Rats, Sprague-Dawley RNA, Messenger - metabolism
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