Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery

A fluorescence confocal microscope incorporating a 1.8-mm-diam gradient-index relay lens is developed for histological guidance during resection of brain tumors. The microscope utilizes a dual-axis confocal architecture to efficiently reject out-of-focus light for high-contrast optical sectioning. A...

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Bibliographic Details
Published in:	Journal of Biomedical Optics Vol. 15; no. 2; p. 026029
Main Authors:	Liu, Jonathan T, Mandella, Michael J, Loewke, Nathan O, Haeberle, Henry, Ra, Hyejun, Piyawattanametha, Wibool, Solgaard, Olav D, Kino, Gordon S, Contag, Christopher H
Format:	Journal Article
Language:	English
Published:	United States Society of Photo-Optical Instrumentation Engineers 01-03-2010
Subjects:	Algorithms Animals Brain Confocal Craniotomy - instrumentation Fluorescence Image Enhancement - instrumentation Lenses Mice Microelectromechanical systems Microscopy, Confocal - instrumentation Miniaturization Relay Reproducibility of Results Research Papers: Imaging Sensitivity and Specificity Surgery, Computer-Assisted - instrumentation
Online Access:	Get full text
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