Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails

Objective: Iron overload and oxidative stress are the major causes of serious complications and mortality in thalassemic patients. Our previous work supports the synergistic effects of antioxidant cocktails (curcuminoids or vitamin E, N-acetylcysteine, and deferiprone) in treatment of β-thalassemia/...

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Bibliographic Details
Published in:	Hematology (Luxembourg) Vol. 24; no. 1; pp. 300 - 307
Main Authors:	Panachan, Jirawan, Chokchaichamnankit, Daranee, Weeraphan, Churat, Srisomsap, Chantragan, Masaratana, Patarabutr, Hatairaktham, Suneerat, Panichkul, Narumol, Svasti, Jisnuson, Kalpravidh, Ruchaneekorn W.
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 01-01-2019
Subjects:	Acetylcysteine - administration & dosage Adult antioxidant beta-Thalassemia - blood beta-Thalassemia - drug therapy Blood Proteins - biosynthesis Curcumin - administration & dosage Curcumin - analogs & derivatives curcuminoids deferiprone Deferiprone - administration & dosage Drug Therapy, Combination Female Free Radical Scavengers - administration & dosage Gene Expression Regulation - drug effects Hemoglobin E Humans Male N-acetylcysteine plasma proteomics thalassemia vitamin E Vitamin E - administration & dosage β-thalassemia/Hb E deferiprone antioxidant plasma proteomics thalassemia β-thalassemia/Hb E vitamin E curcuminoids N-acetylcysteine
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