Wide-Angle Tissue Doppler Imaging at High Frame Rate Using Multi-Line Transmit Beamforming: An Experimental Validation In Vivo

• Published in: IEEE transactions on medical imaging Vol. 35; no. 2; pp. 521 - 528
• Main Authors: Ling Tong, Ramalli, Alessandro, Tortoli, Piero, Fradella, Guiseppe, Caciolli, Sabina, Jianwen Luo, D'hooge, Jan
• Format: Journal Article
• Language: English
• Published: United States IEEE 01-02-2016; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adult; Color; Color tissue Doppler imaging; Correlation coefficient; Doppler; Doppler effect; Echocardiography, Doppler - methods; Frames; Heart Ventricles - diagnostic imaging; high frame rate; Humans; Image color analysis; Image Processing, Computer-Assisted - methods; Image resolution; Imaging; Male; Methodology; Middle Aged; multi-line transmit beam forming; Myocardium; Strain; Temporal resolution; wide-angle field-of-view
• ISSN: 0278-0062; 1558-254X
• DOI: 10.1109/TMI.2015.2480061

Color tissue Doppler imaging (TDI) is a well-established methodology to assess local myocardial motion/deformation. Typically, a frame rate of ~ 200 Hz can be achieved by imaging a narrow sector ( ~ 30 ° , covering one cardiac wall) at moderate line density, using a dedicated pulse sequence and multi-line acquisition. However, a wide angle field-of-view is required in some clinical applications to image the whole left ventricle, which implies a drop in temporal resolution. Hereto, the aim of this study was to propose a novel imaging sequence using a multi-line transmit (MLT) beamforming approach to achieve high frame rate color TDI while preserving a wide field-of-view (i.e., 90 ° sector). To this end, a color MLT-TDI sequence achieving a frame rate of 208 Hz with a 90 ° -sector was implemented on an ultrasound experimental scanner interleaved with a conventional color TDI sequence achieving the same frame rate but only with a 22.5 ° -sector. Using this setup, the septal wall of 9 healthy volunteers was imaged and the corresponding velocity was extracted. The M-mode velocity images and the velocity profiles obtained from the MLT-TDI images presented physiologic patterns, very similar to those from conventional TDI. Moreover, for the peak systolic/diastolic velocities, good agreement and strong correlation between MLT-TDI and conventional TDI were found. The results thus demonstrate the feasibility of the novel MLT based TDI methodology to achieve high frame rate color TDI without compromising the field-of-view. This may open the opportunity to simultaneously assess regional myocardial function of the whole left ventricle at high temporal resolution.