Association between high proviral load, cognitive impairment, and white matter brain lesions in HTLV-1-infected individuals

The association between high proviral load (PVL) in peripheral blood mononuclear cells (PBMC), cognitive disturbance and white matter brain lesions in HTLV-1-infected individuals is still undefined. A cross-sectional study included 62 participants: 22 asymptomatic carriers (mean age 43.4 ± 13.1 year...

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Bibliographic Details
Published in:	Journal of neurovirology Vol. 27; no. 6; pp. 810 - 819
Main Authors:	Kalil, Rosangela Souza, Vasconcellos, Isabelle, Rosadas, Carolina, Cony, Andrea, Lima, Dulcino P., Gonçalves, Cassia C. Alves, Batista, Everton, Grassi, Maria Fernanda, Galvão-Castro, Bernardo, P.Taylor, Graham, Puccioni-Sohler, Marzia
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-12-2021
Subjects:	Adult Biomedical and Life Sciences Biomedicine Brain - diagnostic imaging Child, Preschool Cognitive Dysfunction - diagnostic imaging Cross-Sectional Studies Human T-lymphotropic virus 1 - physiology Humans Immunology Infectious Diseases Leukocytes, Mononuclear Middle Aged Neurology Neurosciences Proviruses - genetics Viral Load Virology White Matter - diagnostic imaging HTLV-1-associated myelopathy Tropical spastic paraparesis HTLV-1 Magnetic resonance imaging Cognitive impairment
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