Kir4.1 channels contribute to astrocyte CO2/H+-sensitivity and the drive to breathe

Astrocytes in the retrotrapezoid nucleus (RTN) stimulate breathing in response to CO 2 /H + , however, it is not clear how these cells detect changes in CO 2 /H + . Considering Kir4.1/5.1 channels are CO 2 /H + -sensitive and important for several astrocyte-dependent processes, we consider Kir4.1/5....

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Bibliographic Details
Published in:	Communications biology Vol. 7; no. 1; pp. 373 - 13
Main Authors:	Cleary, Colin M., Browning, Jack L., Armbruster, Moritz, Sobrinho, Cleyton R., Strain, Monica L., Jahanbani, Sarvin, Soto-Perez, Jaseph, Hawkins, Virginia E., Dulla, Chris G., Olsen, Michelle L., Mulkey, Daniel K.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 28-03-2024 Nature Publishing Group Nature Portfolio
Subjects:	14/19 42/109 42/34 631/443/1784 631/443/376 9/74 Astrocytes Biology Biomedical and Life Sciences Carbon dioxide Genomics Hydrogen Insulin-like growth factors Life Sciences Neuromodulation Neurosciences Paracrine signalling Physiology Potassium channels (inwardly-rectifying) Proteins Respiration Respiratory function Retrotrapezoid nucleus Ventilatory behavior
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