Retinoic acid perturbs Otx gene expression in the ascidian pharynx

In vertebrate embryos, ectopic application of all-trans retinoic acid (RA) alters the expression of Otx genes in the developing midbrain. In conjunction with RA-induced misexpression of other regulatory genes this leads to a loss of anterior CNS. In the ascidian Herdmania curvata, RA primarily inhib...

Full description

Saved in:

Bibliographic Details
Published in:	Development genes and evolution Vol. 210; no. 3; pp. 129 - 139
Main Authors:	Hinman, V F, Degnan, B M
Format:	Journal Article
Language:	English
Published:	Germany Springer Nature B.V 01-03-2000
Subjects:	Animals Ascidiacea Base Sequence DNA Primers DNA, Complementary Gene expression Gene Expression Regulation, Developmental - drug effects Hec-Otx gene Herdmania curvata Homeodomain Proteins - genetics Immunohistochemistry Larva - growth & development Nervous system Otx gene Otx Transcription Factors Pharynx - metabolism Phylogeny RNA, Messenger - genetics Tretinoin - pharmacology Urochordata - embryology Urochordata - growth & development
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!