DNA methylation of PITX2 predicts poor survival in men with prostate cancer

We investigated if methylation of candidate genes can be useful for predicting prostate cancer (PCa) specific death. Methylation of PITX2, WNT5a, SPARC, EPB41L3 and TPM4 was investigated in a 1:2 case-control cohort comprising 45 men with cancer of Gleason score ≤ 7 who died (cases), and 90 men who...

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Bibliographic Details
Published in:	Biomarkers in medicine Vol. 8; no. 9; p. 1143
Main Authors:	Vasiljević, Nataša, Ahmad, Amar S, Carter, Paul D, Fisher, Gabrielle, Berney, Daniel M, Foster, Christopher S, Cuzick, Jack, Lorincz, Attila T
Format:	Journal Article
Language:	English
Published:	England 01-10-2014
Subjects:	Adult Biomarkers, Tumor - metabolism Disease-Free Survival DNA Methylation DNA, Neoplasm - metabolism Follow-Up Studies Homeobox Protein PITX2 Homeodomain Proteins - metabolism Humans Male Middle Aged Neoplasm Proteins - metabolism Prostatic Neoplasms - metabolism Prostatic Neoplasms - mortality Prostatic Neoplasms - pathology Survival Rate Transcription Factors - metabolism DNA methylation prognostic biomarker prostate cancer PITX2
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