In vivo ultrasound modulated optical tomography with a persistent spectral hole burning filter

We present ultrasound modulated optical tomography (UOT) results on mice, using the persistent spectral hole burning (PSHB) effect in a Tm :YAG crystal. Indocyanine green (ICG) solution was injected as an optical absorber and was clearly identified on the PSHB-UOT images, both in the muscle (followi...

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Bibliographic Details
Published in:	Biomedical optics express Vol. 13; no. 12; pp. 6484 - 6496
Main Authors:	Thai, Quang Minh, Kalot, Ghadir, Venet, Caroline, Seguin, Johanne, Bocoum, Maïmouna, Mignet, Nathalie, Ramaz, François, Louchet-Chauvet, Anne
Format:	Journal Article
Language:	English
Published:	United States Optical Society of America - OSA Publishing 01-12-2022 Optica Publishing Group
Subjects:	Physics
Online Access:	Get full text
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Summary:	We present ultrasound modulated optical tomography (UOT) results on mice, using the persistent spectral hole burning (PSHB) effect in a Tm :YAG crystal. Indocyanine green (ICG) solution was injected as an optical absorber and was clearly identified on the PSHB-UOT images, both in the muscle (following an intramuscular injection) and in the liver (following an intravenous injection). This demonstration also validates an experimental setup with an improved level of performance combined with an increased technological maturity compared to previous demonstrations.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2156-7085 2156-7085
DOI:	10.1364/BOE.475449