Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif

Abstract Interrupted dimeric coiled coil segments are found in a broad range of proteins and generally confer selective functional properties such as binding to specific ligands. However, there is only one documented case of a basic-helix–loop–helix leucine zipper transcription factor—microphthalmia...

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Bibliographic Details

Published in:	Nucleic acids research Vol. 48; no. 2; pp. 934 - 948
Main Authors:	Pogenberg, Vivian, Ballesteros-Álvarez, Josué, Schober, Romana, Sigvaldadóttir, Ingibjörg, Obarska-Kosinska, Agnieszka, Milewski, Morlin, Schindl, Rainer, Ögmundsdóttir, Margrét Helga, Steingrímsson, Eiríkur, Wilmanns, Matthias
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 24-01-2020
Subjects:	Animals Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics Cell Nucleus - chemistry Ligands Mice Microphthalmia-Associated Transcription Factor - chemistry Microphthalmia-Associated Transcription Factor - genetics Protein Binding Protein Conformation Protein Domains - genetics Protein Multimerization Structural Biology
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