Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers

Ampakines act as positive allosteric modulators of AMPA-type glutamate receptors and facilitate hippocampal long-term potentiation (LTP), a mechanism associated with memory storage and consolidation. The present study investigated the acute effects of farampator, 1-(benzofurazan-5-ylcarbonyl) piperi...

Full description

Saved in:

Bibliographic Details
Published in:	Neuropsychopharmacology (New York, N.Y.) Vol. 32; no. 6; pp. 1272 - 1283
Main Authors:	WEZENBERG, Elke, JAN VERKES, Robert, RUIGT, Ge S. F, HULSTIJN, Wouter, SABBE, Bernard G. C
Format:	Journal Article
Language:	English
Published:	New York, NY Nature Publishing 01-06-2007 Nature Publishing Group
Subjects:	Adult Adult and adolescent clinical studies Aged Alzheimer's disease Antipsychotics Biological and medical sciences Cognition & reasoning Double-Blind Method Drug dosages Female Humans Information processing Male Maze Learning - drug effects Medical sciences Memory Memory - drug effects Memory, Short-Term - drug effects Mental Processes - drug effects Mental Recall - drug effects Middle Aged Neuropsychological Tests Oxadiazoles - adverse effects Oxadiazoles - blood Oxadiazoles - pharmacology Piperidines - adverse effects Piperidines - blood Piperidines - pharmacology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - drug effects Psychopathology. Psychiatry Psychoses Psychosis Psychotropic drugs Receptors, AMPA - drug effects Saccades - drug effects Schizophrenia Space Perception - drug effects Visual Perception - drug effects Netherlands Psychosis Human ampakine elderly healthy volunteers Healthy subject Acute Memory Information processing Schizophrenia Cognition Elderly Farampator
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!