Intravenous to Oral Switch in Complicated Staphylococcus aureus Bacteremia Without Endovascular Infection: A Retrospective Single-Center Cohort Study

• Published in: Clinical infectious diseases Vol. 73; no. 5; pp. 895 - 898
• Main Authors: Kouijzer, Ilse J E, van Leerdam, Eline J, Gompelman, Michelle, Tuinte, Renee A M, Aarntzen, Erik H J G, Berrevoets, Marvin A H, Maat, Ianthe, Bleeker-Rovers, Chantal P, van Crevel, Reinout, ten Oever, Jaap
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 07-09-2021
• Subjects: Brief Reports; IV-oral switch; treatment; bacteremia; iv-oral switch; Staphylococcus aureus
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1093/cid/ciab156

Abstract
In this retrospective cohort study, selected patients with disseminated Staphylococcus aureus bacteremia, but without endovascular infection on echocardiography and 18F-FDG-PET/CT, were free of relapse after IV-oral switch. Mortality was low and similar to patients who received prolonged intravenous treatment. IV-oral switch was associated with a shorter length of hospital stay.