Effects of prenatal exposure to chronic mild stress and toluene in rats

The aim of the present study was to elucidate whether prenatal chronic stress, in combination with exposure to a developmental neurotoxicant, would increase effects in the offspring compared with the effects of either exposure alone. Development and neurobehavioral effects were investigated in femal...

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Bibliographic Details
Published in:	Neurotoxicology and teratology Vol. 27; no. 1; pp. 153 - 167
Main Authors:	Hougaard, Karin S., Andersen, Maibritt B., Hansen, Åse M., Hass, Ulla, Werge, Thomas, Lund, Søren P.
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01-01-2005 Elsevier Science
Subjects:	Animals Apomorphine - pharmacology Behavior, Animal Biological and medical sciences Body Weight - drug effects Body Weight - physiology CAS no. 108-88-3 Chemical and industrial products toxicology. Toxic occupational diseases Chronic mild stress (CMS) Cognition - drug effects Cognition - physiology Corticosterone - blood Developmental toxicity Dopamine Agonists - pharmacology Dose-Response Relationship, Drug Drug Administration Schedule Drug Interactions Exploratory Behavior - drug effects Exploratory Behavior - physiology Female Gestational Age Interaction Lactation - drug effects Lactation - psychology Male Maze Learning - drug effects Maze Learning - physiology Medical sciences Neural Inhibition - drug effects Neural Inhibition - physiology Organ Size - drug effects Pregnancy Prenatal Exposure Delayed Effects Prenatal stress Rats Reflex, Acoustic - drug effects Reflex, Acoustic - physiology Solvents Solvents - toxicity Startle Stress, Psychological - complications Toluene - toxicity Toxicology Startle CAS no. 108-88-3 Developmental toxicity Chronic mild stress (CMS) Interaction Prenatal stress Rat Toxicity Toluene Rodentia Exposure Stress Prenatal Teratogenesis Organic solvent Vertebrata Chronic Mammalia Animal
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