Prevalence, Incidence and Mortality of Type 2 Diabetes Mellitus Revisited: A Prospective Population-Based Study in The Netherlands (ZODIAC-1)

• Published in: European journal of epidemiology Vol. 18; no. 8; pp. 793 - 800
• Main Authors: Ubink-Veltmaat, L. J., Bilo, H. J. G., Groenier, K. H., Houweling, S. T., Rischen, R. O., Jong, B. Meyboom-de
• Format: Journal Article
• Language: English
• Published: Dordrecht Kluwer Academic Publishers 01-01-2003; Springer; Springer Nature B.V
• Subjects: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Associated diseases and complications; Biological and medical sciences; Child; Child, Preschool; Diabetes; Diabetes complications; Diabetes mellitus; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - mortality; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Epidemiology; Female; General practice; Health care; Humans; Incidence; Infant; Infant, Newborn; Male; Medical sciences; Men; Middle Aged; Mortality; Netherlands - epidemiology; Older adults; Population studies; Population Surveillance; Prevalence; Prospective Studies; Registries; Sex Distribution; Type 1 diabetes mellitus; Type 2 diabetes mellitus; Netherlands; Europe; Endocrinopathy; Type 2 diabetes; Human; Prevalence; Mortality; Diabetes mellitus; Epidemiology; Incidence; Type 2; Prospective study; Public health; Age; Age groups
• ISSN: 0393-2990; 1573-7284
• DOI: 10.1023/A:1025369623365

Background: To present actual data to estimate prevalence, incidence and mortality of known type 2 diabetes mellitus in all age categories in The Netherlands. Methods: Prospective population-based study between 1998 and 2000 in The Netherlands. Baseline population of 155,774 patients, registered with 61 general practitioners participating in the Zwolle Outpatient Diabetes project Integrating Available Care (ZODIAC)-study. Results: Age- and sex-adjusted prevalence of type 2 diabetes was 2.2% at baseline and 2.9% after 2 years of follow-up; for women and men it was 3.1 and 2.7% at follow-up, respectively. Patients aged >70 years account for almost 50% of all type 2 diabetes patients. Age- and sex-adjusted mean annual incidence per 10,000 over 3 years was 22.7 overall; for women 23.1 and for men 22.2. Incidence - even though high - decreases after the age of 70 years. The mortality rate was 47.9/1000 and standardised mortality ratio 1.40. Based on these results, the estimated total number of subjects known with type 2 diabetes was 466,000 for The Netherlands in 2000; the number of patients with newly diagnosed diabetes 36,000. Conclusions: Prevalence and incidence rates exceed all estimates regarding known type 2 diabetes for The Netherlands. Elderly patients, aged 70 years and over, account for 50% of the type 2 diabetic population. These results are important for health-care planning.