Behavioral Effects of Lead and Toxocara canis in Mice

Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequences of Toxocara administrat...

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Published in:	Science (American Association for the Advancement of Science) Vol. 213; no. 4512; pp. 1142 - 1144
Main Authors:	Dolinsky, Z. S., Burright, R. G., Donovick, P. J., Glickman, L. T., Babish, J., Summers, B., Cypess, R. H.
Format:	Journal Article
Language:	English
Published:	United States The American Association for the Advancement Science 04-09-1981 American Association for the Advancement of Science
Subjects:	Animals Ascariasis - complications Axons Behavior, Animal - physiology Boycotts Brain - parasitology Cats Children Disease Models, Animal Diseases Eggs Ganglia Helminths Host-parasite relationships Intubation Larvae Lead in the body Lead Poisoning - complications Lead Poisoning - physiopathology Male Mazes Mice Parasites Pediatric diseases Physiological aspects Toxocariasis - complications Toxocariasis - physiopathology Worms, Intestinal and parasitic
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Abstract	Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequences of Toxocara administration appeared attenuated in animals receiving both agents. Parasite larvae were found in the central nervous system in all infected mice.
AbstractList	Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequence of Toxocara administration appeared attenuated in animals receiving both agents. Parasite larvae were found in the central nervous system in all infected mice. Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequences of Toxocara administration appeared attenuated in animals receiving both agents. Parasite larvae were found in the central nervous system in all infected mice. Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. Consequences of Toxocara administration appeared attenuated in animals receiving both agents. Parasite larvae were found in the central nervous system in all infected mice. Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effcts in mice receiving lead alone were less general. Consequences of Toxocara admininstration appeared attenuated in animals receiving both agents. Parasite larvas were found in the central nervous system in all infected mice.
Audience	Academic
Author	Dolinsky, Z. S. Burright, R. G. Summers, B. Donovick, P. J. Babish, J. Glickman, L. T. Cypess, R. H.
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Cites_doi	10.1016/0361-9230(81)90022-8 10.1002/dev.420070105 10.1093/infdis/135.4.633 10.1289/ehp.747227 10.1016/0035-9203(71)90155-6 10.1542/peds.9.1.7 10.1542/peds.12.5.491
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Snippet	Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration,... Adult mice were administered the common parasite Toxocara canis or lead or both. The parasite clearly altered mouse performance on tests of exploration,...
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SubjectTerms	Animals Ascariasis - complications Axons Behavior, Animal - physiology Boycotts Brain - parasitology Cats Children Disease Models, Animal Diseases Eggs Ganglia Helminths Host-parasite relationships Intubation Larvae Lead in the body Lead Poisoning - complications Lead Poisoning - physiopathology Male Mazes Mice Parasites Pediatric diseases Physiological aspects Toxocariasis - complications Toxocariasis - physiopathology Worms, Intestinal and parasitic
Title	Behavioral Effects of Lead and Toxocara canis in Mice
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