In vitro and in vivo effects of Ranunculus peltatus subsp. baudotii methanol extract on models of eicosanoid production and contact dermatitis

Ranunculus (Crowfoot) species are numerous and they are all reputed to be counter-irritants and are used in several topical conditions. In order to study the pharmacological mechanisms of action underlying this popular use, a methanol extract of Ranunculus peltatus was tested in vitro in various ass...

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Bibliographic Details
Published in:	Phytotherapy research Vol. 22; no. 3; pp. 297 - 302
Main Authors:	Prieto, J.M, Recio, M.C, Giner, R.M, Schinella, G.R, Máñez, S, Ríos, J.L
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-03-2008 Wiley
Subjects:	Animals antiinflammatory activity Biological and medical sciences Cell Survival - drug effects contact dermatitis cyclooxygenase Cyclooxygenase 1 - drug effects Cyclooxygenase 1 - metabolism Dermatitis, Allergic Contact - drug therapy Eicosanoids - biosynthesis Enzyme Inhibitors - pharmacology Enzymes - analysis Enzymes - drug effects Female General pharmacology Humans lipoxygenase Medical sciences Methanol - chemistry Mice Models, Animal Neutrophils - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - pharmacology Ranunculus - chemistry Ranunculus peltatus subsp. baudotii Rats Rats, Wistar Time Factors Prostaglandin-endoperoxide synthase Skin disease Enzyme Pharmacognosy Ranunculaceae Antiinflammatory agent Lipids cyclooxygenase Extract In vitro Ranunculus Medicinal plant Ranunculus peltatus subsp. baudotii Contact dermatitis Dicotyledones Eicosanoid Angiospermae Plant origin Unsaturated fatty acid Herbaceous plant Spermatophyta Oxidoreductases Lipoxygenase antiinflammatory activity
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