Two-month effects of individualized exercise training with or without caloric restriction on plasma adipocytokine levels in obese female adolescents

Résumé Objectifs Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des adipocytokines chez des adolescentes obèses. Matériels et méthodes Vingt-sept adolescentes obèses ont été réparties (ordre randomisé) en trois gro...

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Published in:Annales d'endocrinologie Vol. 70; no. 4; pp. 235 - 241
Main Authors: Ben Ounis, O, Elloumi, M, Lac, G, Makni, E, Van Praagh, E, Zouhal, H, Tabka, Z, Amri, M
Format: Journal Article
Language:English
Published: France Elsevier Masson SAS 01-09-2009
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Abstract Résumé Objectifs Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des adipocytokines chez des adolescentes obèses. Matériels et méthodes Vingt-sept adolescentes obèses ont été réparties (ordre randomisé) en trois groupes avec trois interventions différentes sur deux mois : (1) régime hypocalorique ( n = 9), (2) entraînement individualisé au niveau du Lipoxmax  (puissance pour laquelle le taux d’oxydation des lipides est maximal) ( n = 9) et (3) programme combiné régime/entraînement ( n = 9). La masse corporelle (MC), l’indice de masse corporelle (IMC), le pourcentage de masse grasse (%MG), l’estimation de la résistance à l’insuline par le modèle d’évaluation homéostasique (HOMA-IR) et les niveaux plasmatiques à jeun des adipocytokines ont été évalués avant et après les deux mois d’intervention. Résultats Le programme régime/entraînement a induit un décalage du niveau de Lipoxmax vers une intensité supérieure (+27,8 ± 5,1W ; p < 0,01) et une augmentation de l’oxydation des lipides à Lipoxmax (+96,8 ± 16,2 mg/min ; p < 0,01). L’augmentation de l’oxydation des lipides a été corrélé significativement ( p < 0,01) avec les améliorations induites par le programme régime/entraînement sur le %MG ( r = −0,47), le HOMA-IR ( r = −0,66), la leptine ( r = −0,41), le TNF-α ( r = −0,48), l’Il-6 ( r = −0,38), l’adiponectine ( r = 0,43) et la résistine ( r = 0,51). Conclusion L’entraînement au niveau du Lipoxmax combiné avec un programme de régime hypocalorique a amélioré la capacité à oxyder les lipides pendant l’exercice, et cette amélioration a été associée aux améliorations des niveaux plasmatiques des adipocytokines chez des adolescentes obèses.
AbstractList To examine if, in young obese patients, an individualized training programme in association with a caloric restriction programme which had an effect on whole-body lipid oxidation, was able to induce changes on plasma adipocytokine concentrations. Twenty-seven obese female adolescents participated in the study. Whole-body lipid oxidation during exercise was assessed by indirect calorimetry during a graded cycle ergometer test. Body mass (BM), body mass index (BMI), percentage of body fat (%BF), insulin homeostasis model assessment (HOMA-IR) and fasting levels of circulating adipocytokines were assessed prior and after a two-month diet programme, individualized training programme targeted at Lipox(max) corresponded to the power at which the highest rate of lipids was oxidized and combined diet/training programme. The diet/training programme induced both a shift to a higher-power intensity of Lipox(max) (+27.8 + or - 5.1 W; p<0.01) and an increase of lipid oxidation at Lipox(max) (+96.8 + or - 16.2mg/min; p<0.01). The enhancement in lipid oxidation was significantly (p<0.01) correlated with the diet/training-induced improvement in %BF (r = -0.47), HOMA-IR (r = -0.66), leptin (r = -0.41), TNF-alpha (r = -0.48), IL-6 (r = -0.38), adiponectin (r = 0.43) and resistin (r = 0.51). This study showed that in obese female adolescents a moderate training protocol targeted at Lipox(max) and combined with a diet programme improved their ability to oxidize lipids during exercise, and that this improvement was associated with changes in plasma adipocytokine concentrations.
OBJECTIVESTo examine if, in young obese patients, an individualized training programme in association with a caloric restriction programme which had an effect on whole-body lipid oxidation, was able to induce changes on plasma adipocytokine concentrations.MATERIALS AND METHODSTwenty-seven obese female adolescents participated in the study. Whole-body lipid oxidation during exercise was assessed by indirect calorimetry during a graded cycle ergometer test. Body mass (BM), body mass index (BMI), percentage of body fat (%BF), insulin homeostasis model assessment (HOMA-IR) and fasting levels of circulating adipocytokines were assessed prior and after a two-month diet programme, individualized training programme targeted at Lipox(max) corresponded to the power at which the highest rate of lipids was oxidized and combined diet/training programme.RESULTSThe diet/training programme induced both a shift to a higher-power intensity of Lipox(max) (+27.8 + or - 5.1 W; p<0.01) and an increase of lipid oxidation at Lipox(max) (+96.8 + or - 16.2mg/min; p<0.01). The enhancement in lipid oxidation was significantly (p<0.01) correlated with the diet/training-induced improvement in %BF (r = -0.47), HOMA-IR (r = -0.66), leptin (r = -0.41), TNF-alpha (r = -0.48), IL-6 (r = -0.38), adiponectin (r = 0.43) and resistin (r = 0.51).CONCLUSIONThis study showed that in obese female adolescents a moderate training protocol targeted at Lipox(max) and combined with a diet programme improved their ability to oxidize lipids during exercise, and that this improvement was associated with changes in plasma adipocytokine concentrations.
Résumé Objectifs Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des adipocytokines chez des adolescentes obèses. Matériels et méthodes Vingt-sept adolescentes obèses ont été réparties (ordre randomisé) en trois groupes avec trois interventions différentes sur deux mois : (1) régime hypocalorique ( n = 9), (2) entraînement individualisé au niveau du Lipoxmax  (puissance pour laquelle le taux d’oxydation des lipides est maximal) ( n = 9) et (3) programme combiné régime/entraînement ( n = 9). La masse corporelle (MC), l’indice de masse corporelle (IMC), le pourcentage de masse grasse (%MG), l’estimation de la résistance à l’insuline par le modèle d’évaluation homéostasique (HOMA-IR) et les niveaux plasmatiques à jeun des adipocytokines ont été évalués avant et après les deux mois d’intervention. Résultats Le programme régime/entraînement a induit un décalage du niveau de Lipoxmax vers une intensité supérieure (+27,8 ± 5,1W ; p < 0,01) et une augmentation de l’oxydation des lipides à Lipoxmax (+96,8 ± 16,2 mg/min ; p < 0,01). L’augmentation de l’oxydation des lipides a été corrélé significativement ( p < 0,01) avec les améliorations induites par le programme régime/entraînement sur le %MG ( r = −0,47), le HOMA-IR ( r = −0,66), la leptine ( r = −0,41), le TNF-α ( r = −0,48), l’Il-6 ( r = −0,38), l’adiponectine ( r = 0,43) et la résistine ( r = 0,51). Conclusion L’entraînement au niveau du Lipoxmax combiné avec un programme de régime hypocalorique a amélioré la capacité à oxyder les lipides pendant l’exercice, et cette amélioration a été associée aux améliorations des niveaux plasmatiques des adipocytokines chez des adolescentes obèses.
Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des adipocytokines chez des adolescentes obèses. Vingt-sept adolescentes obèses ont été réparties (ordre randomisé) en trois groupes avec trois interventions différentes sur deux mois : (1) régime hypocalorique ( n = 9), (2) entraînement individualisé au niveau du Lipox max (puissance pour laquelle le taux d’oxydation des lipides est maximal) ( n = 9) et (3) programme combiné régime/entraînement ( n = 9). La masse corporelle (MC), l’indice de masse corporelle (IMC), le pourcentage de masse grasse (%MG), l’estimation de la résistance à l’insuline par le modèle d’évaluation homéostasique (HOMA-IR) et les niveaux plasmatiques à jeun des adipocytokines ont été évalués avant et après les deux mois d’intervention. Le programme régime/entraînement a induit un décalage du niveau de Lipox max vers une intensité supérieure (+27,8 ± 5,1W ; p < 0,01) et une augmentation de l’oxydation des lipides à Lipox max (+96,8 ± 16,2 mg/min ; p < 0,01). L’augmentation de l’oxydation des lipides a été corrélé significativement ( p < 0,01) avec les améliorations induites par le programme régime/entraînement sur le %MG ( r = −0,47), le HOMA-IR ( r = −0,66), la leptine ( r = −0,41), le TNF-α ( r = −0,48), l’Il-6 ( r = −0,38), l’adiponectine ( r = 0,43) et la résistine ( r = 0,51). L’entraînement au niveau du Lipox max combiné avec un programme de régime hypocalorique a amélioré la capacité à oxyder les lipides pendant l’exercice, et cette amélioration a été associée aux améliorations des niveaux plasmatiques des adipocytokines chez des adolescentes obèses. To examine if, in young obese patients, an individualized training programme in association with a caloric restriction programme which had an effect on whole-body lipid oxidation, was able to induce changes on plasma adipocytokine concentrations. Twenty-seven obese female adolescents participated in the study. Whole-body lipid oxidation during exercise was assessed by indirect calorimetry during a graded cycle ergometer test. Body mass (BM), body mass index (BMI), percentage of body fat (%BF), insulin homeostasis model assessment (HOMA-IR) and fasting levels of circulating adipocytokines were assessed prior and after a two-month diet programme, individualized training programme targeted at Lipox max corresponded to the power at which the highest rate of lipids was oxidized and combined diet/training programme. The diet/training programme induced both a shift to a higher-power intensity of Lipox max (+27.8 ± 5.1 W; p < 0.01) and an increase of lipid oxidation at Lipox max (+96.8 ± 16.2 mg/min; p < 0.01). The enhancement in lipid oxidation was significantly ( p < 0.01) correlated with the diet/training-induced improvement in %BF ( r = −0.47), HOMA-IR ( r = −0.66), leptin ( r = −0.41), TNF-α ( r = −0.48), IL-6 ( r = −0.38), adiponectin ( r = 0.43) and resistin ( r = 0.51). This study showed that in obese female adolescents a moderate training protocol targeted at Lipox max and combined with a diet programme improved their ability to oxidize lipids during exercise, and that this improvement was associated with changes in plasma adipocytokine concentrations.
Author Lac, G
Tabka, Z
Makni, E
Ben Ounis, O
Elloumi, M
Zouhal, H
Amri, M
Van Praagh, E
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/19403116$$D View this record in MEDLINE/PubMed
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DocumentTitleAlternate Effets d’un programme de deux mois d’entraînement individualisé associé ou non à un régime hypocalorique sur les niveaux plasmatiques des adipocytokines chez des adolescentes obèses
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Adipocytokines
Restriction calorique
Physical activity
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Snippet Résumé Objectifs Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des...
Étudier les effets d’un programme d’entraînement individualisé associé à un régime hypocalorique sur les concentrations plasmatiques des adipocytokines chez...
To examine if, in young obese patients, an individualized training programme in association with a caloric restriction programme which had an effect on...
OBJECTIVESTo examine if, in young obese patients, an individualized training programme in association with a caloric restriction programme which had an effect...
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SubjectTerms Activité physique
Adipocytokines
Adipokines - blood
Adolescence obesity
Adolescent
Adolescentes obèses
Body Mass Index
Caloric restriction
Caloric Restriction - methods
Combined Modality Therapy
Cytokines - blood
Endocrinology & Metabolism
Exercise
Female
Humans
Internal Medicine
Lipids - physiology
Obesity - blood
Obesity - rehabilitation
Physical activity
Restriction calorique
Skinfold Thickness
Weight Loss
Title Two-month effects of individualized exercise training with or without caloric restriction on plasma adipocytokine levels in obese female adolescents
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https://dx.doi.org/10.1016/j.ando.2009.03.003
https://www.ncbi.nlm.nih.gov/pubmed/19403116
https://search.proquest.com/docview/733861972
Volume 70
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