Patency of Endovascular Treatment for Central Venous Stenosis: Is There a Difference Between Dialysis Fistulas and Grafts?

• Published in: Journal of vascular and interventional radiology Vol. 18; no. 3; pp. 353 - 359
• Main Authors: Rajan, Dheeraj K., MD, FRCPC, Chennepragada, S. Murthy, MBBS, Lok, Charmaine E., MD, FRCPC, Beecroft, J. Robert, MD, FRCPC, Tan, Kong T., FRCS, FRCR, FRCPC, Hayeems, Eran, MD, FRCPC, Kachura, John R., MD, FRCPC, Sniderman, Kenneth W., MD, Simons, Martin E., MD, FRCPC
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-03-2007
• Subjects: Adult; Aged; Aged, 80 and over; Angioplasty; Blood Vessel Prosthesis; Cohort Studies; Constriction, Pathologic - surgery; Female; Humans; Male; Middle Aged; Radiology; Renal Dialysis; Retrospective Studies; Stents; Transplants; Treatment Outcome; Vascular Diseases - surgery; Vascular Fistula - surgery; Vascular Patency; Veins - surgery; CVS; SVC; superior vena cava; DSA; central venous stenosis; digital subtraction angiography
• ISSN: 1051-0443; 1535-7732
• DOI: 10.1016/j.jvir.2007.01.012

Purpose To determine if there is a difference in intervention patency for central venous stenosis (CVS) and occlusion between patients with autogenous hemodialysis fistulas and those with grafts. Material and Methods A retrospective study was performed from March 1998 to September 2005 identifying all patients with autogenous fistulas and synthetic grafts who underwent percutaneous angioplasty and/or stent placement for CVS. This study cohort consisted of 38 patients (22 with fistulas and 16 with grafts). Age, sex, type of access, location and side of the access, location and side of the CVS, presence of diabetes, previous hemodialysis catheter placement, date and type of interventions, and outcomes were recorded. The patency of each intervention was estimated by using the Kaplan-Meier survival curves. Univariate and multivariate analysis of the variables were performed. Results Eighty-nine interventions were performed; 83 were angioplasties and six were stent placements. Previous catheter placement on the side of the CVS occurred in 29 of the 38 patients (76%). Technical and clinical success of the interventions were 93.3% and 94.4% respectively. The intervention or primary patency rates ± standard errors at 3, 6, and 9 months in the fistula group were 88.5% ± 4.8, 59.4% ± 7.6, and 46% ± 7.9, respectively. In the graft group, the rates were 78.1% ± 7.3, 40.7% ± 9, and 16% ± 7.3, respectively. With multivariate analysis, intervention patency remained significantly longer for fistulas ( P = .014) and in patients who did not have a previous catheter ( P = .001). Conclusion Longer intervention-free survival for CVS was observed in patients with autogenous fistulas compared with grafts and in patients who did not previously undergo hemodialysis catheter insertion.