Altered serum glyceraldehyde-derived advanced glycation end product (AGE) and soluble AGE receptor levels indicate carbonyl stress in patients with schizophrenia

•Advanced glycation end product (AGE) is a carbonyl stress marker of schizophrenia.•Glycer-AGE and receptors for AGE (sRAGE) were involved in neurotoxic pathology.•We compared serum these markers levels between schizophrenia and controls.•Glycer-AGEs and sRAGE levels were significantly higher and lo...

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Bibliographic Details
Published in:	Neuroscience letters Vol. 593; pp. 51 - 55
Main Authors:	Takeda, Mayu, Ohnuma, Tohru, Takeuchi, Masayoshi, Katsuta, Narimasa, Maeshima, Hitoshi, Takebayashi, Yuto, Higa, Motoyuki, Nakamura, Toru, Nishimon, Shohei, Sannohe, Takahiro, Hotta, Yuri, Hanzawa, Ryo, Higashiyama, Ryoko, Shibata, Nobuto, Gohda, Tomohito, Suzuki, Yusuke, Yamagishi, Sho-ichi, Tomino, Yasuhiko, Arai, Heii
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 23-04-2015
Subjects:	Adolescent Adult Aged Biomarkers - blood Carbonyl stress Case-Control Studies Clinical course Female Glycation End Products, Advanced - blood Glycer-AGEs Glyceraldehyde - metabolism Humans Male Middle Aged Receptor for Advanced Glycation End Products Receptors, Immunologic - blood Schizophrenia Schizophrenia - blood Schizophrenia - diagnosis sRAGE DSM-IV Glycer-AGE Carbonyl stress Schizophrenia Glycer-AGEs RAGE esRAGE BPRS ANCOVA MMP Clinical course sRAGE AGE BMI ELISA
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