Metabolic impact of obesity in childhood

Childhood and adolescent obesity have become the most prevalent nutritional diseases in the United States. The results of a number of studies demonstrate that the metabolic alterations caused by excess body fat are expressed early in the natural history of obesity. Such alterations seem clinically i...

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Bibliographic Details
Published in:	Endocrinology and metabolism clinics of North America Vol. 28; no. 4; p. 731
Main Authors:	Caprio, S, Tamborlane, W V
Format:	Journal Article
Language:	English
Published:	United States 01-12-1999
Subjects:	Adolescent Adult Blood Glucose - metabolism Body Composition Child Female Humans Insulin - metabolism Insulin - pharmacology Insulin Secretion Islets of Langerhans - physiopathology Leptin - metabolism Male Obesity - metabolism Obesity - physiopathology
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Summary:	Childhood and adolescent obesity have become the most prevalent nutritional diseases in the United States. The results of a number of studies demonstrate that the metabolic alterations caused by excess body fat are expressed early in the natural history of obesity. Such alterations seem clinically important even in children, as evidenced by the recent increase in type 2 diabetes in obese adolescents. These observations underscore the need for research efforts directed at the development of effective interventions to stem the tide of the childhood obesity epidemic.
ISSN:	0889-8529
DOI:	10.1016/S0889-8529(05)70099-2