Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support

Abstract Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing...

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Bibliographic Details
Published in:	Clinical infectious diseases Vol. 70; no. 6; pp. 1222 - 1225
Main Authors:	Winchester, Nicole E, Maldarelli, Frank, Mejia, Yolanda, Dee, Nicola, Dewar, Robin, Laidlaw, Elizabeth, Kuriakose, Safia S, Stoll, Pamela, Proschan, Michael, Lane, H Clifford, Pau, Alice K
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 03-03-2020
Subjects:	Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active Brief Reports Directly Observed Therapy Drug Resistance, Viral HIV Infections - drug therapy HIV-1 Humans Inpatients Medication Adherence Treatment Failure Viral Load viral failure directly observed therapy drug resistance antiretroviral therapy adherence
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Summary:	Abstract Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing unnecessary regimen changes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/ciz590