LL-37 treatment on human peripheral blood mononuclear cells modulates immune response and promotes regulatory T-cells generation

LL-37 is a host-defense peptide (HDP) and exerts a broad spectrum of microbicidal activity against bacteria, fungi, and viral pathogens. This peptide also interacts with human cells and influences their behavior, promoting angiogenesis, wound healing, immunomodulation, and affecting apoptosis. Latel...

Full description

Saved in:

Bibliographic Details
Published in:	Biomedicine & pharmacotherapy Vol. 108; pp. 1584 - 1590
Main Authors:	Alexandre-Ramos, Dominique Sternadt, Silva-Carvalho, Amandda Évelin, Lacerda, Mariella Guimarães, Serejo, Teresa Raquel Tavares, Franco, Octávio Luiz, Pereira, Rinaldo Wellerson, Carvalho, Juliana Lott, Neves, Francisco Assis Rocha, Saldanha-Araujo, Felipe
Format:	Journal Article
Language:	English
Published:	France Elsevier Masson SAS 01-12-2018
Subjects:	Adult Anti-Bacterial Agents - pharmacology Antimicrobial Cationic Peptides - pharmacology Cells, Cultured Flow Cytometry - methods Humans Immune response Immunity, Cellular - drug effects Immunity, Cellular - immunology Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology LL-37 PBMCs T-cells T-Lymphocytes, Regulatory - drug effects T-Lymphocytes, Regulatory - immunology Tregs T-cells LL-37 Immune response PBMCs Tregs
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!