Analysis of the transcription of genes encoding heat shock proteins (hsp) in Aedes aegypti Linnaeus, 1762 (Diptera: Culicidae), maintained under climatic conditions provided by the IPCC (Intergovernmental Panel On Climate Change) for the year 2100

• Published in: Infection, genetics and evolution Vol. 86; p. 104626
• Main Authors: do Nascimento Neto, Joaquim Ferreira, da Mota, Adolfo José, Roque, Rosemary Aparecida, Heinrichs-Caldas, Waldir, Tadei, Wanderli Pedro
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-12-2020
• Subjects: Amazon; Environmental room; Global warming; Microcosm; Vectors; Environmental room; Global warming; Vectors; Amazon; Microcosm
• ISSN: 1567-1348; 1567-7257
• DOI: 10.1016/j.meegid.2020.104626

Human actions intensify the greenhouse effect, aggravating climate changes in the Amazon and elsewhere in the world. The Intergovernmental Panel on Climate Change (IPCC) foresees a global increase of up to 4.5 °C and 850 ppm CO2 (above current levels) by 2100. This will impact the biology of the Aedes aegypti mosquito, vector of Dengue, Zika, urban Yellow Fever and Chikungunya. Heat shock proteins are associated with adaptations to anthropic environments and the interaction of some viruses with the vector. The transcription of the hsp26, hsp83 and hsc70 genes of an A. aegypti population, maintained for more than forty-eight generations, in the Current, Intermediate and Extreme climatic scenario predicted by the IPCC was evaluated with qPCR. In females, highest levels of hsp26, hsp83 and hsc70 expression occurred in the Intermediate scenario, while in males, levels were high only for hsp26 gene in Current and Extreme scenarios. Expression of hsp83 and hsc70 genes in males was low under all climatic scenarios, while in the Extreme scenario females had lower expression than in the Current scenario. The data suggest compensatory or adaptive processes acting on heat shock proteins, which can lead to changes in the mosquito's biology, altering vectorial competence.
•Climate change influence the life of mosquito vectors in the environment•The expression of non-heat shock genes may be involved in environmental adaptation•Many generations of A. aegypti exposed to climatic stress stabilize Hsp expression•Greenhouse effect alters the transcription of Heat shock genes in vector.