Extrahepatic Manifestations of Hepatitis C Virus After Liver Transplantation

• Published in: Clinics in liver disease Vol. 21; no. 3; pp. 595 - 606
• Main Authors: Wong, Robert J., MD, MS, Saab, Sammy, MD, MPH, Ahmed, Aijaz, MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-08-2017
• Subjects: Cardiovascular Diseases - epidemiology; Chronic kidney disease; Cryoglobulinemia - epidemiology; Diabetes mellitus; Diabetes Mellitus - epidemiology; Gastroenterology and Hepatology; Health-related quality of life; Hepatitis C, Chronic - complications; Hepatitis C, Chronic - epidemiology; Humans; Insulin Resistance; Kidney Diseases - epidemiology; Liver Transplantation; Lymphoproliferative disorders; Lymphoproliferative Disorders - epidemiology; Non-alcoholic Fatty Liver Disease - epidemiology; Postoperative Period; Quality of Life; Health-related quality of life; Chronic kidney disease; Lymphoproliferative disorders; Diabetes mellitus; Liver transplantation
• ISSN: 1089-3261; 1557-8224
• DOI: 10.1016/j.cld.2017.03.013

Chronic hepatitis C virus (HCV) infection remains a leading cause of chronic liver disease in the United States. Although the hepatic impact of chronic HCV leading to cirrhosis and the need for liver transplantation is paramount, the extrahepatic manifestations of chronic HCV are equally important. In particular, a better understanding of the prevalence and impact of extrahepatic manifestations of chronic HCV in the post-liver transplant setting relies on understanding the interplay between the effects of chronic HCV among a posttransplant environment characterized by strong immunosuppression and the associated risks of this milieu.