Structural insights into eRF3 and stop codon recognition by eRF1

Eukaryotic translation termination is mediated by two interacting release factors, eRF1 and eRF3, which act cooperatively to ensure efficient stop codon recognition and fast polypeptide release. The crystal structures of human and Schizosaccharomyces pombe full-length eRF1 in complex with eRF3 lacki...

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Bibliographic Details
Published in:	Genes & development Vol. 23; no. 9; pp. 1106 - 1118
Main Authors:	Cheng, Zhihong, Saito, Kazuki, Pisarev, Andrey V, Wada, Miki, Pisareva, Vera P, Pestova, Tatyana V, Gajda, Michal, Round, Adam, Kong, Chunguang, Lim, Mengkiat, Nakamura, Yoshikazu, Svergun, Dmitri I, Ito, Koichi, Song, Haiwei
Format:	Journal Article
Language:	English
Published:	United States Cold Spring Harbor Laboratory Press 01-05-2009
Subjects:	Adenosine Triphosphate - metabolism Codon, Terminator - metabolism Gene Order GTP Phosphohydrolases - metabolism Humans Models, Molecular Mutation Peptide Termination Factors - chemistry Peptide Termination Factors - genetics Protein Binding Protein Biosynthesis - genetics Protein Structure, Quaternary Protein Structure, Tertiary Reproducibility of Results Research Paper Ribosomes - metabolism Scattering, Small Angle Schizosaccharomyces - genetics Schizosaccharomyces - metabolism Schizosaccharomyces pombe Proteins - chemistry
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