Occurrence and recurrence of basal cell carcinoma of the head and neck in Negroid and albinoid Africans

• Published in: Journal of laryngology and otology Vol. 101; no. 12; p. 1324
• Main Authors: Ademiluyi, S A, Ijaduola, G T
• Format: Journal Article
• Language: English
• Published: England 01-12-1987
• Subjects: African Continental Ancestry Group; Albinism - complications; Albinism - pathology; Carcinoma, Basal Cell - complications; Carcinoma, Basal Cell - epidemiology; Carcinoma, Basal Cell - pathology; Female; Head and Neck Neoplasms - complications; Head and Neck Neoplasms - epidemiology; Head and Neck Neoplasms - pathology; Humans; Male; Neoplasm Recurrence, Local; Nigeria; Nigeria
• ISSN: 0022-2151
• DOI: 10.1017/S0022215100103780

A study of sixty patients with basal cell carcinoma of the head and neck region carried out over a six-year period (1979-1985) is hereby presented. Sixteen (26.72 per cent) were albinos and 44 (73.28 per cent) negroids. Forty-eight (80 per cent) were outdoor workers. The negroid patients presented between the 3rd and 4th decades while the albinos presented a decade earlier. The commonest site involved in the head and neck was the forehead. The midface showed the highest recurrence rate in both groups, even after adequate excision. The frequency of recurrence in tumours presenting with a size of 2-5 cm. diameter was significantly higher in the albinos than in the negroid (P less than 0.05), whereas, with tumours of a size larger than 5 cm., there was no statistically significant difference between the albino and the negroid. However, the overall recurrence rate was significantly higher in the albinos (P less than 0.005). The mortality among the albinos was 25 per cent while there were no deaths in the negroid Africans.