LY294002 Enhances Inhibitory Effect of Gemcitabine on Proliferation of Human Pancreatic Carcinoma PANC-1 Cells

Phosphatidylinositide 3-kinase (PI3K)/protein kinase B (PKB, Akt) pathway plays a major role in proliferation and survival of many types of cells. The inhibitory effect of LY294002, widely ap- plied as an inhibitor of PI3K, in combination with gemcitabine on proliferation of PANC-1 ceils was investi...

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Published in:Journal of Huazhong University of Science and Technology. Medical sciences Vol. 33; no. 1; pp. 57 - 62
Main Author: 柯晓煜 王渝 谢祚启 刘志清 张翠芳 赵秋 杨东亮
Format: Journal Article
Language:English
Published: Heidelberg Huazhong University of Science and Technology 01-02-2013
Department of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China%Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China%Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022, China
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