Santa Clara de Nanay: The MAL-ED Cohort in Peru

• Published in: Clinical infectious diseases Vol. 59; no. suppl_4; pp. S310 - S316
• Main Authors: Yori, Pablo Peñataro, Lee, Gwenyth, Olórtegui, Maribel Paredes, Chávez, César Banda, Flores, Julian Torres, Vasquez, Angel Orbe, Burga, Rosa, Pinedo, Silvia Rengifo, Asayag, César Ramal, Black, Robert E., Caulfield, Laura E., Kosek, Margaret
• Format: Journal Article
• Language: English
• Published: United States OXFORD UNIVERSITY PRESS 01-11-2014; Oxford University Press
• Subjects: Adolescent; Adult; Aged; Ascaris; Bacteria; Campylobacter; Child; Child nutrition disorders; Child Nutrition Disorders - epidemiology; Child, Preschool; Childrens health; Communicable Diseases - epidemiology; Diarrhea; Epidemiologic Research Design; Epidemiology; Escherichia coli; Female; Fertility; Giardia; Helminthiasis; HIV; Human immunodeficiency virus; Humans; Infant; Infant, Newborn; Longitudinal Studies; Malaria; Male; Malnutrition; Malnutrition - epidemiology; Measles mumps rubella vaccines; Middle Aged; Mycobacterium; Peru - epidemiology; Population characteristics; Risk factors; Shigella; Tuberculosis; Yellow fever vaccines; Young Adult; Peru; Peru, Loreto, Iquitos; Mexico, Baja California Sur, Loreto; ISE, Peru; MAL-ED; malnutrition; birth cohort; Peru
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1093/cid/ciu460

The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study communities in Peru are located in Loreto province, in a rural area 15 km from the city of Iquitos. This riverine population of approximately 5000 individuals is fairly representative of Loreto. The province lags behind the rest of the country in access to water and sanitation, per capita income, and key health indicators including infant mortality (43.0 vs 16.0 per 1000 nationwide) and under-5 mortality (60.6 vs 21.0 per 1000). Total fertility rates are higher than elsewhere in the country (4.3 vs 2.6). Nationwide, the prevalence of human immunodeficiency virus is estimated at 0.45%, the prevalence of tuberculosis is 117 per 100 000, and the incidence of malaria is 258 per 100 000. Stunting in this community is high, whereas acute undernutrition is relatively uncommon. The population suffers from high rates of diarrheal disease. Prevalent enteric pathogens include Ascaris, Giardia, enterotoxigenic Escherichia coli, Shigella, and Campylobacter.