Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis

• Published in: Materials Vol. 12; no. 6; p. 986
• Main Authors: Hadush Tesfay, Abadi, Chou, Yu-Jen, Tan, Cheng-Yan, Fufa Bakare, Fetene, Tsou, Nien-Ti, Huang, E-Wen, Shih, Shao-Ju
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25-03-2019; MDPI
• Subjects: Aluminosilicates; Aluminum silicates; Biodegradability; Bioglass; Biological activity; Fourier transforms; Ion beams; Materials science; Morphology; Nanoparticles; Nitrates; Radiation therapy; Radioisotopes; Scanning electron microscopy; Spectrum analysis; Spray pyrolysis; Studies; Temperature effects; Yttrium; Ceram; United Kingdom > UK; United States > US; Japan; Taiwan; electron microscopy; bioactive glass; Yttrium; spray pyrolysis
• ISSN: 1996-1944; 1996-1944
• DOI: 10.3390/ma12060986

In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain in the host body for a long duration after treatment. The preparation of Y-doped BG powders were carried out using a spray pyrolysis method. By using two different yttrium sources, we examine the change of the local distribution of yttrium concentration. In addition, characterizations of phase information, particle morphologies, surface areas, and bioactivity were also performed. The results show that both Y-doped BG powders are bioactive and the local Y distribution can be controlled.