Investigation of the occurrence of a contraceptive tetrapeptide in hamster embryos

Investigation of the occurrence of a contraceptive tetrapeptide in hamster embryos

The synthetic tetrapeptide H-Thr-Pro-Lys-OH, the extract of two-cell hamster embryos, and the oviductal contents devoid of embryos failed to show any in vivo antifertility activity. In addition, the tetrapeptide was not found in the biologic preparations of embryo extract and remaining oviductal con...

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Bibliographic Details
Published in:Fertility and sterility Vol. 29; no. 6; p. 686
Main Authors: Palekar, A G, Stolzenberg, S J, Madan, S M
Format: Journal Article
Language:English
Published: United States 01-06-1978
Subjects:
Animals
Cricetinae
Embryo, Mammalian - analysis
Fallopian Tubes - analysis
Female
Fertility - drug effects
Oligopeptides - analysis
Oligopeptides - pharmacology
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Description
Summary:The synthetic tetrapeptide H-Thr-Pro-Lys-OH, the extract of two-cell hamster embryos, and the oviductal contents devoid of embryos failed to show any in vivo antifertility activity. In addition, the tetrapeptide was not found in the biologic preparations of embryo extract and remaining oviductal contents. These findings are not in agreement with those of previous reports.
ISSN:0015-0282
DOI:10.1016/S0015-0282(16)43346-7