Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18

• Published in: Wellcome open research Vol. 3; p. 67
• Main Authors: Cook, Sarah, Malyutina, Sofia, Kudryavtsev, Alexander V, Averina, Maria, Bobrova, Natalia, Boytsov, Sergey, Brage, Soren, Clark, Taane G., Diez Benavente, Ernest, Eggen, Anne Elise, Hopstock, Laila A, Hughes, Alun, Johansen, Heidi, Kholmatova, Kamila, Kichigina, Anastasiya, Kontsevaya, Anna, Kornev, Michael, Leong, Darryl, Magnus, Per, Mathiesen, Ellisiv, McKee, Martin, Morgan, Katy, Nilssen, Odd, Plakhov, Ilya, Quint, Jennifer K, Rapala, Alicja, Ryabikov, Andrey, Saburova, Lyudmila, Schirmer, Henrik, Shapkina, Marina, Shiekh, Suhail, Shkolnikov, Vladimir M, Stylidis, Michael, Voevoda, Michael, Westgate, Kate, Leon, David A
• Format: Journal Article
• Language: English
• Published: London Wellcome Trust Limited 2018; F1000 Research Limited; Wellcome
• Subjects: Alcohol; Biomarkers; Cardiovascular disease; Cholesterol; Cross-sectional studies; Funding; Genotype & phenotype; Heart; Mens health; Mortality; Objectives; Population; Risk factors; Roles; Software; Studies; Study Protocol; Supervision; Trends; Womens health; Writing; Norway; Russia
• ISSN: 2398-502X; 2398-502X
• DOI: 10.12688/wellcomeopenres.14619.3

Russia has one of the highest rates of cardiovascular disease in the world. The International Project on Cardiovascular Disease in Russia (IPCDR) was set up to understand the reasons for this. A substantial component of this study was the Know Your Heart Study devoted to characterising the nature and causes of cardiovascular disease in Russia by conducting large cross-sectional surveys in two Russian cities Novosibirsk and Arkhangelsk. The study population was 4542 men and women aged 35-69 years recruited from the general population. Fieldwork took place between 2015-18. There were two study components: 1) a baseline interview to collect information on socio-demographic characteristics and cardiovascular risk factors, usually conducted at home, and 2) a comprehensive health check at a primary care clinic which included detailed examination of the cardiovascular system. In this paper we describe in detail the rationale for, design and conduct of these studies.