Intramuscular Injection of Expression Plasmid DNA Is an Effective Means of Long-Term Systemic Delivery of Interleukin-5

It has been demonstrated that intramuscularly injected expression plasmid DNA is taken up by myofibers and subsequently expresses exogenous genes. In the present study, we assessed intramuscular DNA injection as a means of systemically delivering interleukin-5 (IL-5). We constructed an IL-5 expressi...

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Bibliographic Details

Published in:	Biochemical and biophysical research communications Vol. 233; no. 2; pp. 527 - 531
Main Authors:	Tokui, Mikiya, Takei, Izumi, Tashiro, Fumi, Shimada, Akira, Kasuga, Akira, Ishii, Masatoshi, Ishii, Toshiharu, Takatsu, Kiyoshi, Saruta, Takao, Miyazaki, Jun-ichi
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 17-04-1997
Subjects:	Animals Female Gene Transfer Techniques Injections, Intramuscular Interleukin-5 - genetics Mice Mice, Inbred C57BL Plasmids - genetics Polymerase Chain Reaction RNA, Messenger - metabolism
Online Access:	Get full text
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