Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus)

Mule deer fawns (Odocoileus hemionus) were inoculated orally with a brain homogenate prepared from mule deer with naturally occurring chronic wasting disease (CWD), a prion-induced transmissible spongiform encephalopathy. Fawns were necropsied and examined for PrP(res), the abnormal prion protein is...

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Bibliographic Details
Published in:	Journal of general virology Vol. 80; no. 10; pp. 2757 - 2764
Main Authors:	Sigurdson, C.J, Williams, E.S, Miller, M.W, Spraker, T.R, O'Rourke, K.I, Hoover, E.A
Format:	Journal Article
Language:	English
Published:	England Soc General Microbiol 01-10-1999
Subjects:	Animals Chronic Disease Deer disease transmission Lymphoid Tissue - metabolism prion diseases Prion Diseases - etiology Prion Diseases - pathology Prion Diseases - veterinary Prions - analysis Staining and Labeling Time Factors Tissue Distribution Wasting Syndrome - etiology Wasting Syndrome - pathology Wasting Syndrome - veterinary
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