Preoperatively determinable factors predictive of diabetes mellitus remission following Roux-en-Y gastric bypass: a review of the literature

• Published in: Acta diabetologica Vol. 50; no. 4; pp. 475 - 478
• Main Authors: Adams, ST, Salhab, M., Hussain, ZI, Miller, GV, Leveson, SH
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01-08-2013; Springer Nature B.V
• Subjects: Clinical outcomes; Diabetes; Diabetes Mellitus, Type 2 - surgery; Gastric Bypass; Gastrointestinal surgery; Humans; Internal Medicine; Medicine; Medicine & Public Health; Metabolic Diseases; Obesity; Predictive Value of Tests; Preoperative Period; Review Article; Obesity; Bypass; Diabetes
• ISSN: 0940-5429; 1432-5233
• DOI: 10.1007/s00592-013-0453-2

It is well established that weight loss in general and bariatric surgery in particular can improve glycaemic control in diabetics. Current NICE guidelines recommend that those patients with type 2 diabetes mellitus and a BMI of 35 kg/m
2
or more should be considered for bariatric surgery in order to optimise their glycaemic control and minimise their risk of long-term complications. The commonest bariatric procedure in the UK is the Roux-en-Y gastric bypass that has been shown to result in long-standing type 2 diabetes resolution in 83 % of patients. Since such surgery carries a small but significant risk of mortality, as well as posing considerable lifestyle implications for the patient, numerous studies have been performed with a view to identifying which patients and which procedures are most likely to result in these desired benefits. This paper summarises the existing literature on this topic.