[3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain

The specific binding of [3H]8-hydroxy-2-(di-n-propylamino)tetralin ([ 3H]8-OH-DPAT) to 5-hydroxytryptamine (5-HT)-related sites was investigated in several regions of the rat brain. Marked differences were observed in the characteristics of binding to membranes from hippocampus, striatum, and cerebr...

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Bibliographic Details
Published in:	Journal of neurochemistry Vol. 44; no. 6; p. 1685
Main Authors:	Hall, M D, el Mestikawy, S, Emerit, M B, Pichat, L, Hamon, M, Gozlan, H
Format:	Journal Article
Language:	English
Published:	England 01-06-1985
Subjects:	5,7-Dihydroxytryptamine - pharmacology 8-Hydroxy-2-(di-n-propylamino)tetralin Animals Binding Sites Biogenic Amines - pharmacology Brain - metabolism Cations - pharmacology In Vitro Techniques Kainic Acid - pharmacology Kinetics Male Naphthalenes - metabolism Nucleotides - pharmacology Rats Rats, Inbred Strains Receptors, Serotonin - metabolism Reserpine - pharmacology Serotonin - metabolism Tetrahydronaphthalenes - metabolism Tritium
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