Molecular functions of ANKLE2 and its implications in human disease

Ankyrin repeat and LEM domain-containing 2 (ANKLE2) is a scaffolding protein with established roles in cell division and development, the dysfunction of which is increasingly implicated in human disease. ANKLE2 regulates nuclear envelope disassembly at the onset of mitosis and its reassembly after c...

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Bibliographic Details

Published in:	Disease models & mechanisms Vol. 17; no. 4
Main Authors:	Fishburn, Adam T, Florio, Cole J, Lopez, Nick J, Link, Nichole L, Shah, Priya S
Format:	Journal Article
Language:	English
Published:	England The Company of Biologists Ltd 01-04-2024 The Company of Biologists
Subjects:	Animals cell division Disease DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Humans microcephaly Mutation - genetics neurodevelopment Nuclear Proteins - metabolism Review Cell division Neurodevelopment Microcephaly
Online Access:	Get full text
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