Heterogeneous disease: A child case of lichen planus pemphigoides triggered by varicella

• Published in: Journal of dermatology Vol. 38; no. 7; pp. 707 - 710
• Main Authors: İLKNUR, Turna, AKARSU, Sevgi, UZUN, Soner, ÖZER, Erdener, FETIL, Emel
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-07-2011
• Subjects: Basement membranes; Bullous pemphigoid; Chickenpox - complications; Child; Complement C3 - metabolism; Female; Humans; Immunofluorescence; Immunoglobulin G; Immunoglobulin G - metabolism; Lichen planus; Lichen Planus - etiology; Lichen Planus - immunology; Lichen Planus - pathology; lichen planus pemphigoides; Pemphigoid, Bullous - etiology; Pemphigoid, Bullous - immunology; Pemphigoid, Bullous - pathology; Skin; subepidermal blistering disorder; Varicella
• ISSN: 0385-2407; 1346-8138
• DOI: 10.1111/j.1346-8138.2011.01220.x

Lichen planus pemphigoides (LPP) is a rare and controversial disease. It is characterized clinically by tense bullae arising both on lichen planus papules and on uninvolved skin, histologically by the demonstration of subepidermal bullae and by linear deposits of immunoglobulin G and C3 along the basement membrane zone on immunofluorescence of peribullous skin. Some authors consider LPP as the combination of lichen planus and bullous pemphigoid. Others think that it most likely encompasses a heterogeneous group of subepidermal autoimmune blistering disorders occurring in association with lichen planus. We present a child case that supports the heterogeneous condition of this disease triggered by varicella.